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Titolo:
Prostate histopathology and the chronic prostatitis/chronic pelvic pain syndrome: A prospective biopsy study
Autore:
True, LD; Berger, RE; Rothman, I; Ross, SO; Krieger, JN;
Indirizzi:
Univ Washington, Med Ctr, Dept Pathol, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 , Dept Pathol, Seattle, WA 98195 USA Univ Washington, Med Ctr, Dept Urol, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 tr, Dept Urol, Seattle, WA 98195 USA
Titolo Testata:
JOURNAL OF UROLOGY
fascicolo: 6, volume: 162, anno: 1999,
pagine: 2014 - 2018
SICI:
0022-5347(199912)162:6<2014:PHATCP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEN;
Keywords:
prostatitis; pelvic pain; inflammation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: True, LD Univ Washington, Med Ctr, Dept Pathol, Seattle, WA 98195 USA UnivWashington Seattle WA USA 98195 thol, Seattle, WA 98195 USA
Citazione:
L.D. True et al., "Prostate histopathology and the chronic prostatitis/chronic pelvic pain syndrome: A prospective biopsy study", J UROL, 162(6), 1999, pp. 2014-2018

Abstract

Purpose: The chronic prostatitis/chronic pelvic pain syndrome is a common clinical syndrome characterized by lower genitourinary tract symptoms, particularly pain in the perineum or genitalia, voiding symptoms, such as dysuria or frequency, and sexual dysfunction in the absence of uropathogens in the urine or prostatic secretions. The term prostatitis is based on the presumption that prostatic inflammation is important in the pathophysiology of this syndrome. To our knowledge there has been no systematic characterization of the degree and nature of inflammation in the prostate in symptomatic cases. Materials and Methods: Prostate histopathology in 368 biopsies from 97 patients with the chronic prostatitis/chronic pelvic pain syndrome was characterized.. Results: Prostatic inflammation was detected in only 33% of patients, including 29% with mild (less than 10 leukocytes per I mm. field) and 4% with moderate (between 10 and 200) or severe (more than 200)infiltrate. Of the 3 patients with moderate inflammation 1 had glandular, 1 periglandular and 3 multifocal or diffuse distribution of leukocytes in the interstitium Some patients had more than I pattern of inflammation. Conclusions: The finding of moderate or severe inflammation in only 5% of 97 patients argues for the need to reevaluate current concepts of the pathophysiology of the chronic prostatitis/ chronic pelvic pain syndrome.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 19:13:05