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Titolo:
Lipid-lowering medication and risk of injury
Autore:
Bovbjerg, VE; Siscovick, DS; Psaty, BM; McCann, BS; Koepsell, TD; Raghunathan, TE; Wagner, EH;
Indirizzi:
Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA 23298 USA Virginia Commonwealth Univ Richmond VA USA 23298 , Richmond, VA 23298 USA Virginia Commonwealth Univ, Dept Biostat, Richmond, VA 23298 USA Virginia Commonwealth Univ Richmond VA USA 23298 , Richmond, VA 23298 USA Virginia Commonwealth Univ, Dept Hlth Adm, Richmond, VA 23298 USA VirginiaCommonwealth Univ Richmond VA USA 23298 , Richmond, VA 23298 USA Univ Washington, Dept Med, Seattle, WA USA Univ Washington Seattle WA USA niv Washington, Dept Med, Seattle, WA USA Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 ept Hlth Serv, Seattle, WA 98195 USA Univ Washington, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 t & Behav Sci, Seattle, WA 98195 USA Univ Michigan, Inst Social Res, Ann Arbor, MI 48109 USA Univ Michigan AnnArbor MI USA 48109 Social Res, Ann Arbor, MI 48109 USA Grp Hlth Cooperat Puget Sound, Ctr Hlth Studies, Seattle, WA USA Grp Hlth Cooperat Puget Sound Seattle WA USA th Studies, Seattle, WA USA
Titolo Testata:
JOURNAL OF CLINICAL EPIDEMIOLOGY
fascicolo: 12, volume: 52, anno: 1999,
pagine: 1197 - 1200
SICI:
0895-4356(199912)52:12<1197:LMAROI>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLESTEROL; PREVENTION;
Keywords:
anticholesterolemic agents; cholesterol; lipoproteins; injury; coronary disease; case-control study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Bovbjerg, VE Univ Virginia, Hlth Sci Ctr, Sch Med, Box 600, Charlottesville, VA 22908 USA Univ Virginia Box 600 Charlottesville VA USA 22908 22908 USA
Citazione:
V.E. Bovbjerg et al., "Lipid-lowering medication and risk of injury", J CLIN EPID, 52(12), 1999, pp. 1197-1200

Abstract

Meta-analyses of early primary prevention trials of lipid-lowering therapies suggested increased risk of injury deaths among treated persons. Our population-based case-control study examined the association of lipid-loweringmedication use with fatal and nonfatal injuries in 298 cases and 332 controls. No increased injury risk was observed among current (OR = 0.46, 95% CI0.18-1.21) or past users (OR = .92, 95% CI 0.44-1.95), after adjustment for behavioral disorders, medical conditions, and health status. Stratified analyses did not reveal sub-groups at significantly increased risk. These results, consistent with recent clinical trials and meta-analyses, suggest noincreased injury risk associated with lipid-lowering medications. (C) Elsevier Science, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:22:56