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Titolo:
Xanthomatous hypophysitis: A novel entity of obscure etiology
Autore:
Deodhare, SS; Bilbao, JM; Kovacs, K; Horvath, E; Nomikos, P; Buchfelder, M; Reschke, K; Lehnert, H;
Indirizzi:
Univ Toronto, St Michaels Hosp, Dept Lab Med, Toronto, ON M5B 1W8, Canada Univ Toronto Toronto ON Canada M5B 1W8 b Med, Toronto, ON M5B 1W8, Canada Univ Erlangen Nurnberg, Dept Neurosurg, D-8520 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-8520 D-8520 Erlangen, Germany Univ Magdeburg, Dept Endocrinol, D-39106 Magdeburg, Germany Univ Magdeburg Magdeburg Germany D-39106 nol, D-39106 Magdeburg, Germany
Titolo Testata:
ENDOCRINE PATHOLOGY
fascicolo: 3, volume: 10, anno: 1999,
pagine: 237 - 241
SICI:
1046-3976(199923)10:3<237:XHANEO>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DISEASE;
Keywords:
pituitary; hypophysitis; differential diagnosis; immunohistochemistry; electron microscopy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Deodhare, SS St Michaels Hosp, Dept Pathol, 2C,30 Bond St, Toronto, ON M5B1W8, Canada St Michaels Hosp 2C,30 Bond St Toronto ON Canada M5B 1W8 nada
Citazione:
S.S. Deodhare et al., "Xanthomatous hypophysitis: A novel entity of obscure etiology", ENDOCR PATH, 10(3), 1999, pp. 237-241

Abstract

We report a case of xanthomatous hypophysitis, a recently described entityof obscure etiology affecting the pituitary gland, in a 43-yr-old woman. Histologically it is characterized by infiltration of the anterior pituitaryby foamy histiocytes which are strongly immunoreactive for CD68 (histiocytic marker) and are immunonegative for S100 and CD1a. Electron microscopy revealed histiocytes with abundant cytoplasmic lipid droplets and membrane bound vacuoles. Fragments of intact anterior pituitary with preserved vascular and reticulin networks are seen. Xanthomatous hypophysitis resembles neoplasm on clinical and radiologic grounds.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:02:55