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Titolo:
Inflammatory pseudotumor of the liver in a patient with chronic hepatitis C: Difficulty in differentiating it from hepatocellular carcinoma
Autore:
Kim, SR; Hayashi, Y; Kudo, M; Matsuoka, T; Imoto, S; Sasaki, K; Shintani, S; Song, KB; Park, SY; Kim, JH; Ando, K; Koterazawa, T; Kim, KI; Ninomiya, T;
Indirizzi:
Kobe Asahi Hosp, Dept Gastroenterol, Nagata Ku, Kobe, Hyogo 6530801, JapanKobe Asahi Hosp Kobe Hyogo Japan 6530801 a Ku, Kobe, Hyogo 6530801, Japan Kobe Asahi Hosp, Dept Pharm, Kobe, Hyogo 6530801, Japan Kobe Asahi Hosp Kobe Hyogo Japan 6530801 harm, Kobe, Hyogo 6530801, Japan Kobe Univ, Sch Med, Dept Pathol 1, Kobe, Hyogo 650, Japan Kobe Univ Kobe Hyogo Japan 650 Med, Dept Pathol 1, Kobe, Hyogo 650, Japan Kinki Univ, Sch Med, Dept Internal Med 2, Sayama, Osaka, Japan Kinki UnivSayama Osaka Japan Dept Internal Med 2, Sayama, Osaka, Japan Osaka City Univ, Sch Med, Dept Radiol, Osaka 545, Japan Osaka City Univ Osaka Japan 545 , Sch Med, Dept Radiol, Osaka 545, Japan Kobe Univ, Sch Med, Dept Internal Med 2, Kobe, Hyogo 650, Japan Kobe UnivKobe Hyogo Japan 650 ept Internal Med 2, Kobe, Hyogo 650, Japan
Titolo Testata:
PATHOLOGY INTERNATIONAL
fascicolo: 8, volume: 49, anno: 1999,
pagine: 726 - 730
SICI:
1320-5463(199908)49:8<726:IPOTLI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
PSEUDOLYMPHOMA; MICROBUBBLES; ANGIOGRAPHY; DIAGNOSIS; CHILD; TUMOR;
Keywords:
CO2 ultrasound angiography; hepatocellular carcinoma; inflammatory pseudotumor; pseudolymphoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, SR Kobe Asahi Hosp, Dept Gastroenterol, Nagata Ku, 3-5-25 Bouoji Cho,Kobe, Hyogo 6530801, Japan Kobe Asahi Hosp 3-5-25 Bouoji Cho Kobe Hyogo Japan 6530801 , Japan
Citazione:
S.R. Kim et al., "Inflammatory pseudotumor of the liver in a patient with chronic hepatitis C: Difficulty in differentiating it from hepatocellular carcinoma", PATHOL INT, 49(8), 1999, pp. 726-730

Abstract

A case of an inflammatory pseudotumor of the liver in a 75-year-old femalewith chronic hepatitis C whose radiologic features simulated that of hepatocellular carcinoma (HCC) is presented. On imaging studies, hypervascularity by CO2 ultrasound (US) angiography, enhancement at an early phase and isodensity at a late phase by incremental dynamic computed tomography (CT), perfusion defect by CT during arteriography (CTAP), and clinical background of hepatitis C virus (HCV) infection strongly suggested HCC. A US-guided needle biopsy revealed a mainly diffuse and polyclonal proliferation of lymphocytes positive for leukocyte common antigen (pan-lymphocyte cells), L-26 (Bcell lymphocytes), and UCHL-1 (T cell lymphocytes), negative for both x and lambda light chains and sparsely distributed neutrophils and histiocytes. No lymphoid follicles were observed. The liver tissue around this tumor showed chronic hepatitis with mild activity and mild fibrosis. These histopathologic findings suggested that the diagnosis of inflammatory pseudotumor of the liver was tenable. As it is difficult to differentiate between inflammatory pseudotumor of the liver and HCC by imaging studies alone, supplemental biopsy, where possible, should be obtained when diagnostic imaging of tumors suggesting HCC is carried out. We emphasize that histopathology is a true gold standard in the diagnosis of this disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 17:49:54