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Titolo:
The dynein heavy chain gene family in Tetrahymena thermophila
Autore:
Xu, WJ; Royalty, MP; Zimmerman, JR; Angus, SP; Pennock, DG;
Indirizzi:
Miami Univ, Dept Zool, Oxford, OH 45056 USA Miami Univ Oxford OH USA 45056 iami Univ, Dept Zool, Oxford, OH 45056 USA
Titolo Testata:
JOURNAL OF EUKARYOTIC MICROBIOLOGY
fascicolo: 6, volume: 46, anno: 1999,
pagine: 606 - 611
SICI:
1066-5234(199911/12)46:6<606:TDHCGF>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
OUTER-ARM DYNEIN; BETA-HEAVY; CHLAMYDOMONAS-REINHARDTII; PARAMECIUM-TETRAURELIA; CYTOPLASMIC EXCHANGE; SEQUENCE-ANALYSIS; MOTOR PROTEINS; BINDING SITES; ALPHA-DYNEIN; EXPRESSION;
Keywords:
axoneme; cell motility; cilia; ciliate; dynein arm; inner dynein arm; outer dynein arm;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Pennock, DG Miami Univ, Dept Zool, Oxford, OH 45056 USA Miami Univ OxfordOH USA 45056 ept Zool, Oxford, OH 45056 USA
Citazione:
W.J. Xu et al., "The dynein heavy chain gene family in Tetrahymena thermophila", J EUKAR MIC, 46(6), 1999, pp. 606-611

Abstract

The dynein ATPases are a family of motor enzymes that drive microtubule sliding in cilia and flagella and contribute to microtubule-based transport inside cells. The multi-dynein hypothesis makes two predictions: 1) Axonemescontain multiple dynein heavy chain (DHC) isoforms, each encoded by a different gene; 2) Each isoform performs a specific role in ciliary beating. Weused PCR-based techniques to clone thirteen different DHC sequences from Tetrahymena genomic DNA. All thirteen genes appeared to be expressed in growing cells. Comparisons of the deduced amino acid sequences of the thirteen DHCs with other known DHCs suggested that we have cloned three outer arm DHCs, two cytoplasmic DHCs, and eight inner arm DHCs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 22:57:59