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Titolo:
Determination of urinary orotic acid and uracil by capillary zone electrophoresis
Autore:
Salerno, C; DEufemia, P; Celli, M; Finocchiaro, R; Crifo, C; Giardini, O;
Indirizzi:
Univ Rome La Sapienza, Inst Paediat, Clin Biochem Lab, I-00185 Rome, ItalyUniv Rome La Sapienza Rome Italy I-00185 iochem Lab, I-00185 Rome, Italy Univ Rome La Sapienza, Dept Biochem Sci, I-00185 Rome, Italy Univ Rome La Sapienza Rome Italy I-00185 iochem Sci, I-00185 Rome, Italy
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 1, volume: 734, anno: 1999,
pagine: 175 - 178
SICI:
1387-2273(19991029)734:1<175:DOUOAA>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
UREA CYCLE; HYPERAMMONEMIA; DISORDERS; CHROMATOGRAPHY; DEFICIENCY; PROTEINS; PURINE;
Keywords:
ortic acid; uracil;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Salerno, C Univ Rome La Sapienza, Inst Paediat, Clin Biochem Lab, PiazzaleAldo Moro 5, I-00185 Rome, Italy Univ Rome La Sapienza Piazzale Aldo Moro 5 Rome Italy I-00185
Citazione:
C. Salerno et al., "Determination of urinary orotic acid and uracil by capillary zone electrophoresis", J CHROMAT B, 734(1), 1999, pp. 175-178

Abstract

We describe a simple method for measuring orotic acid and uracil concentration in urine by capillary zone electrophoresis in 20 mM Na-borate buffer, pH 9.2. The method was applied for studying a patient with HHH (hyperornithinemia, hyperammonemia and homocitrullinuria) syndrome. A high value of uracil excretion was found during periods of relatively low orotic acid excretion and normal ammonemia. The orotic acid level in urine was increased by increasing protein intake. (C) 1999 Elsevier Science B.V. All rights reserved.

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Documento generato il 31/10/20 alle ore 01:50:30