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Titolo:
Different patterns of chronic tissue wasting among patients with chronic obstructive pulmonary disease
Autore:
Engelen, MPKJ; Schols, AMWJ; Lamers, RJS; Wouters, EFM;
Indirizzi:
Univ Hosp Maastricht, Dept Pulmonol, NL-6202 AZ Maastricht, Netherlands Univ Hosp Maastricht Maastricht Netherlands NL-6202 AZ icht, Netherlands
Titolo Testata:
CLINICAL NUTRITION
fascicolo: 5, volume: 18, anno: 1999,
pagine: 275 - 280
SICI:
0261-5614(199910)18:5<275:DPOCTW>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; DUAL-PHOTON-ABSORPTIOMETRY; CLINICALLY STABLE PATIENTS; LEAN BODY-MASS; NUTRITIONAL DEPLETION; COMPUTED-TOMOGRAPHY; ENERGY-EXPENDITURE; EMPHYSEMA; COPD; QUANTIFICATION;
Keywords:
lean mass; bone mineral mass; fat mass; chronic bronchitis; emphysema;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Engelen, MPKJ Univ Hosp Maastricht, Dept Pulmonol, POB 5800, NL-6202 AZ Maastricht, Netherlands Univ Hosp Maastricht POB 5800 Maastricht NetherlandsNL-6202 AZ
Citazione:
M.P.K.J. Engelen et al., "Different patterns of chronic tissue wasting among patients with chronic obstructive pulmonary disease", CLIN NUTR, 18(5), 1999, pp. 275-280

Abstract

Background & aims: Nutritional depletion is frequently present in patientswith chronic obstructive pulmonary disease, but it is unknown whether a difference exists between the two subtypes. The aim of this study was to determine whether patterns of tissue depletion were different between emphysemaand chronic bronchitis patients and whether these were related to pulmonary function. Methods: In 99 severe COPD patients and 28 healthy volunteers, body weightand composition were assessed by dual-energy X-ray absorptiometry. Patients were stratified into chronic bronchitis (n=50) and emphysema (n=49) by high-resolution computed tomography. Results: Lean mass depletion was found in 37% of the emphysema patients and in 12% of the chronic bronchitis patients. The emphysema patients had lower values for body mass index than the other groups (P< 0.01), mainly due to a lower lean mass (P< 0.01) and bone mineral content (P< 0.01). Fat mass was also lower in the emphysema group compared to the chronic bronchitis group (P< 0.001). The chronic bronchitis patients had a higher fat mass (P< 0.05) and a lower bone mineral content (P< 0.01) than the healthy volunteers. Conclusions: Substantial differences in body composition were found not only between chronic obstructive pulmonary disease patients and healthy volunteers, but also between chronic bronchitis and emphysema patients. (C) 1999Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 03:20:38