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Titolo:
O'nyong-nyong fever in south-central Uganda, 1996-1997: Clinical features and validation of a clinical case definition for surveillance purposes
Autore:
Kiwanuka, N; Sanders, EJ; Rwaguma, EB; Kawamata, J; Ssengooba, FP; Najjemba, R; Were, WA; Lamunu, M; Bagambis, G; Burkot, TR; Dunster, L; Lutwama, JJ; Martin, DA; Cropp, CB; Karabatsos, N; Lanciotti, RS; Tsai, TF; Campbell, GL;
Indirizzi:
Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Natl Ctr Infect Dis, Publ Hlth Serv,US Dept Hlth & Human Serv, Ft Collins, CO 80522 USA Ctr Dis Control & Prevent Ft Collins CO USA 80522 t Collins, CO 80522 USA Uganda Virus Res Inst, Entebbe, Uganda Uganda Virus Res Inst Entebbe Uganda da Virus Res Inst, Entebbe, Uganda Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Natl Ctr Infect Dis, Publ Hlth Serv,US Dept Hlth & Human Serv, San Juan, PR USA Ctr Dis Control & Prevent San Juan PR USA & Human Serv, San Juan, PR USA CDC, Epidem Intelligence Serv, Epidemiol Program Off, Atlanta, GA 30333 USA CDC Atlanta GA USA 30333 rv, Epidemiol Program Off, Atlanta, GA 30333 USA WHO, Div Emerging & Other Communicable Dis Surveillanc, CH-1211 Geneva, Switzerland WHO Geneva Switzerland CH-1211 Surveillanc, CH-1211 Geneva, Switzerland Makerere Univ, Inst Publ Hlth, Kampala, Uganda Makerere Univ Kampala Uganda rere Univ, Inst Publ Hlth, Kampala, Uganda Rakai Dist Med Off, Rakai, Uganda Rakai Dist Med Off Rakai UgandaRakai Dist Med Off, Rakai, Uganda Kenya Med Res Inst, Nairobi, Kenya Kenya Med Res Inst Nairobi KenyaKenya Med Res Inst, Nairobi, Kenya
Titolo Testata:
CLINICAL INFECTIOUS DISEASES
fascicolo: 5, volume: 29, anno: 1999,
pagine: 1243 - 1250
SICI:
1058-4838(199911)29:5<1243:OFISU1>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
ST-LOUIS ENCEPHALITIS; EPIDEMIC POLYARTHRITIS; MONOCLONAL-ANTIBODIES; VIRUS; IDENTIFICATION; AUSTRALIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Campbell, GL Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Natl Ctr Infect Dis, Publ Hlth Serv,US Dept Hlth & Human Serv, POB 2087, Ft Collins, CO 80522USA Ctr Dis Control & Prevent POB 2087 Ft Collins CO USA 80522SA
Citazione:
N. Kiwanuka et al., "O'nyong-nyong fever in south-central Uganda, 1996-1997: Clinical features and validation of a clinical case definition for surveillance purposes", CLIN INF D, 29(5), 1999, pp. 1243-1250

Abstract

O'nyong-nyong (ONN) fever, caused by infection with a mosquito-borne central African alphavirus, is an acute, nonfatal illness characterized by polyarthralgia, During 1996-1997, south-central Uganda experienced the second ONN fever epidemic ever recognized. Among 391 persons interviewed and sampled, 40 cases of confirmed and 21 of presumptive, well-characterized acute, recent, or previous ONN fever were identified through active case-finding efforts or during a household serosurvey and by the application of clinical and laboratory criteria. Among confirmed cases, the knees and ankles were thejoints most commonly affected. The median duration of arthralgia was 6 days (range, 2-21 days) and of immobilization was 4 days (range, 1-14 days). In the majority, generalized skin rash was reported, and nearly half had lymphadenopathy, mainly of the cervical region. Viremia was documented in 16 cases, primarily during the first 3 days of illness, and in some of these, body temperature was normal. During this epidemic, the combination of fever,arthralgia, and lymphadenopathy had a specificity of 83% and a sensitivityof 61% in the identification of cases of ONN fever and thus could be useful for surveillance purposes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 14:54:20