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Titolo:
Managing pediatric epilepsy syndromes with new antiepileptic drugs
Autore:
Pellock, JM;
Indirizzi:
Virginia Commonwealth Univ, Med Coll Virginia, Comprehens Epilepsy Ctr, Div Child Neurol, Richmond, VA 23298 USA Virginia Commonwealth Univ RichmondVA USA 23298 , Richmond, VA 23298 USA
Titolo Testata:
PEDIATRICS
fascicolo: 5, volume: 104, anno: 1999,
pagine: 1106 - 1116
SICI:
0031-4005(199911)104:5<1106:MPESWN>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLEX PARTIAL SEIZURES; REFRACTORY PARTIAL EPILEPSY; PARTIAL-ONSET SEIZURES; RESISTANT PARTIAL SEIZURES; PLACEBO-CONTROLLED TRIAL; LENNOX-GASTAUT-SYNDROME; ADD-ON THERAPY; SECONDARILY GENERALIZED SEIZURES; NEWLY-DIAGNOSED EPILEPSY; DOSE-RANGING TRIAL;
Keywords:
epilespy; pediatrics; antiepileptic drugs;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
125
Recensione:
Indirizzi per estratti:
Indirizzo: Pellock, JM Virginia Commonwealth Univ, Med Coll Virginia, Comprehens Epilepsy Ctr, Div Child Neurol, Randolph Minor Hall,7th Floor,307 Coll St, Richmond, VA 23298 USA Virginia Commonwealth Univ Randolph Minor Hall,7th Floor,307 Coll St Richmond VA USA 23298
Citazione:
J.M. Pellock, "Managing pediatric epilepsy syndromes with new antiepileptic drugs", PEDIATRICS, 104(5), 1999, pp. 1106-1116

Abstract

The management of epilepsy in the pediatric patient requires careful evaluation, classification, and pharmacologic treatment. Despite best efforts onthe part of clinicians, approximately 25% of children remain refractory toappropriate medical therapies. The development of an improved classification system and the emergence of several new antiepileptic drugs have enabledsome progress in this area, specifically in children with disorders such as Lennox-Gastaut syndrome and infantile spasms, which are notoriously difficult to control. However, limited data are available that define the optimal use of new antiepileptic agents in pediatric patients. To most effectively treat children with epilepsy syndromes, further research must be completed to validate the positive effects described in case reports, open-label clinical trials, and early controlled clinical trials.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:26:51