Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Phylogenetic analysis of a retroposon family in African great apes
Autore:
Kim, HS; Wadekar, RV; Takenaka, O; Hyun, BH; Crow, TJ;
Indirizzi:
Univ Oxford, Warneford Hosp, Dept Psychiat, POWIC, Oxford OX3 7JX, EnglandUniv Oxford Oxford England OX3 7JX chiat, POWIC, Oxford OX3 7JX, England Kyoto Univ, Primate Res Inst, Dept Cellular & Mol Biol, Inuyama, Aichi 484, Japan Kyoto Univ Inuyama Aichi Japan 484 & Mol Biol, Inuyama, Aichi 484, Japan Korea Res Inst Biosci & Biotechnol, Genet Resources Ctr, Taejon, South Korea Korea Res Inst Biosci & Biotechnol Taejon South Korea ejon, South Korea
Titolo Testata:
JOURNAL OF MOLECULAR EVOLUTION
fascicolo: 5, volume: 49, anno: 1999,
pagine: 699 - 702
SICI:
0022-2844(199911)49:5<699:PAOARF>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOLUTION; ELEMENTS; SINE;
Keywords:
retroposons; great apes; SINE-R.C2; HERV-K LTRs; phylogeny; hominoid evolution;
Tipo documento:
Letter
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Crow, TJ Univ Oxford, Warneford Hosp, Dept Psychiat, POWIC, Oxford OX3 7JX, England Univ Oxford Oxford England OX3 7JX WIC, Oxford OX3 7JX, England
Citazione:
H.S. Kim et al., "Phylogenetic analysis of a retroposon family in African great apes", J MOL EVOL, 49(5), 1999, pp. 699-702

Abstract

The SINE-R retroposon family has been identified by its relationship with the long terminal ret peats (LTRs) of human endogenous retrovirus class K (HERV-K) as a mobile element that has evolved recently in the human genome. Here we examined the recent evolutionary history of this class of elements by a:PCF: approach to genomic DNA from the African great apes and by phylogenetic analysis including comparison with the HERV K10 parent sequence. With primers derived from a cDNA sequence from human brain, we identified 27 sequences from the chimpanzee and 16 from the gorilla. Phylogenetic comparisons with previously recognized sequences from the human and from the orangutan and gibbon revealed wide overlap of elements across species, suggestingmultiple origins in the course of hominoid evolution. Two human elements SINE-R.C2 and HS307 were the furthest removed from the HERV-K10 sequence butthese two elements were closely related to three elements from the chimpanzee and four elements from the gorilla. This group of elements (our clusters 14 and 15) appears to have transposed late in hominoid evolution. One element (Ch-M16) showed 99.1% sequence identity with the SLNE-R.C2 element, which is human-specific. Thus the SINE-R family appears to have continued to be active in transposition throughout the course of primate evolution.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 01:59:49