Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Changes in renal function during weight loss induced by high vs low-protein low-fat diets in overweight subjects
Autore:
Skov, AR; Toubro, S; Bulow, J; Krabbe, K; Parving, HH; Astrup, A;
Indirizzi:
Royal Vet & Agr Univ, Res Dept Human Nutr, DK-1958 Copenhagen C, Denmark Royal Vet & Agr Univ Copenhagen Denmark C DK-1958 Copenhagen C, Denmark Bispebjerg Hosp, Dept Clin Physiol, DK-2400 Copenhagen, Denmark BispebjergHosp Copenhagen Denmark DK-2400 , DK-2400 Copenhagen, Denmark Steno Diabet Ctr, DK-2820 Gentofte, Denmark Steno Diabet Ctr Gentofte Denmark DK-2820 Ctr, DK-2820 Gentofte, Denmark
Titolo Testata:
INTERNATIONAL JOURNAL OF OBESITY
fascicolo: 11, volume: 23, anno: 1999,
pagine: 1170 - 1177
SICI:
0307-0565(199911)23:11<1170:CIRFDW>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLOMERULAR-FILTRATION RATE; AMINO-ACID INFUSION; HEALTHY-SUBJECTS; MEAT MEAL; HEMODYNAMICS; RESTRICTION; KIDNEYS; DISEASE; HUMANS;
Keywords:
dietary proteins; intervention studies; glomerular filtration rate; obesity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Astrup, A Royal Vet & Agr Univ, Res Dept Human Nutr, Rolighedsvej 30, DK-1958 Copenhagen C, Denmark Royal Vet & Agr Univ Rolighedsvej 30 Copenhagen Denmark C nmark
Citazione:
A.R. Skov et al., "Changes in renal function during weight loss induced by high vs low-protein low-fat diets in overweight subjects", INT J OBES, 23(11), 1999, pp. 1170-1177

Abstract

BACKGROUND: Due to the high satiating effect of protein, a high-protein diet may be desirable in the treatment of obesity, However the long-term effect of different levels of protein intake on renal function is unclear. OBJECTIVE: To assess the renal effects of high vs low protein contents in fat-reduced diets. DESIGN: Randomized 6 months dietary intervention study comparing two controlled ad libitum diets with 30 energy (E%) fat content: high-protein (HP; 25 E%) or low-protein, (LP, 12 E% protein), All food was provided by self-selection in a shop at the department, and high compliance to the diet composition was confirmed by measurements of urinary nitrogen excretion. SUBJECTS: 65 healthy, overweight and obese (25 < body mass index (BMI) < 34 kg/m(2)). RESULTS: Dietary protein intake changed from 91.1 gld to a 6 months intervention average of 70.4 g/d (P < 0.05) in the LP group and from 91.4 g/d to 107.8 g/d (P < 0.05) in the HP group, producing changes in glomular filtration rate (GFR) of - 7.1 ml/min in the LP group and + 5.2 ml/min in the HP group (group effect: P < 0.05). Kidney volume decreased by - 6.2 cm(3) in the HP group and increased by + 9.1 cm(3) in the HP group (P < 0.05), whereasalbuminuria remained unchanged in all groups. CONCLUSION: Moderate changes in dietary protein intake cause adaptive alterations in renal size and function without indications of adverse effects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:57:51