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Titolo:
Structured diagnostic assessment and depot fluphenazine treatment of multiple suicide attempters in the emergency department
Autore:
Battaglia, J; Wolff, TK; Wagner-Johnson, DS; Rush, AJ; Carmody, TJ; Basco, MR;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Psychiat, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 d Ctr, Dept Psychiat, Dallas, TX 75235 USA Univ Texas, SW Med Ctr, Acad Comp Serv, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 Ctr, Acad Comp Serv, Dallas, TX 75235 USA Univ Texas, SW Med Ctr, Dept Psychol, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 ed Ctr, Dept Psychol, Dallas, TX 75235 USA Alaska Psychiat Inst, Anchorage, AK USA Alaska Psychiat Inst Anchorage AKUSA a Psychiat Inst, Anchorage, AK USA
Titolo Testata:
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
fascicolo: 6, volume: 14, anno: 1999,
pagine: 361 - 372
SICI:
0268-1315(199911)14:6<361:SDAADF>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BORDERLINE PERSONALITY-DISORDER; SELF-INJURIOUS-BEHAVIOR; CONTROLLED INTERVENTION; CLOZAPINE TREATMENT; CLINICAL INTERVIEW; SUBSTANCE-ABUSE; MUTILATION; DEPRESSION; PHARMACOTHERAPY; HALOPERIDOL;
Keywords:
attempted suicide; borderline personality disorder; fluphenazine; psychiatry emergency services; self-destructive behaviour; self-injurious behaviour; suicide;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
66
Recensione:
Indirizzi per estratti:
Indirizzo: Wolff, TK Univ Texas, SW Med Ctr, Dept Psychiat, 5323 Harry Hines Blvd, Dallas, TX 75235 USA Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75235 X 75235 USA
Citazione:
J. Battaglia et al., "Structured diagnostic assessment and depot fluphenazine treatment of multiple suicide attempters in the emergency department", INT CLIN PS, 14(6), 1999, pp. 361-372

Abstract

The aim of this study was to compare the efficacy of two doses of monthly intramuscular (i.m.) injections of fluphenazine decanoate in reducing self-harm behaviours in outpatients with histories of multiple suicide attempts. Fifty-eight patients who presented to a psychiatric emergency service after an attempted suicide and who had histories of multiple suicide attempts, were randomized to receive monthly i.m, injections of fluphenazine decanoate. Thirty patients received monthly 12.5 mg ('low' dose), and 28 patients received monthly 1.5 mg ('ultra low' dose) under double-blind conditions. DSM-III-R diagnoses were obtained on all patients using the Structured Clinical Interview for DSM-III-R-Patient Version (SCID-P) and SCID for DSM-III-R Personality Disorders (SCID-II). Outcomes were assessed by the Parasuicide History Inventory and the Abnormal Involuntary Movement Scale, collected monthly for 6 months. Patients had an average of six current Axis I and 2.6 Axis II diagnoses, with borderline personality (85%) and alcohol dependence (58%) occurring most frequently in the sample. Both the low dose and ultra-low dose groups showed a marked reduction in self-harm behaviours. For 'serious' self harm behaviours, there was a trend for a greater effect of the low dose over the ultra-low dose group, however, the differences did not reach statistical significance. A survival analysis indicated that the presence of 'acute' stressors at baseline and female sex were risk factors for continuing (post-randomization) 'serious' self-harm behaviours, while younger age and the absence of concurrent general medical conditions were risk factors for all self-harm behaviours. Int Clin Psychopharmacol 14:361-372 (C) 1999 Lippincott Williams & Wilkins.

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Documento generato il 03/04/20 alle ore 07:44:08