Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Commissural NTS lesions and cardiovascular responses in aortic baroreceptor-denervated rats
Autore:
Sato, MA; Menani, JV; Lopes, OU; Colombari, E;
Indirizzi:
Univ Fed Sao Paulo, Escola Paulista Med, Dept Physiol, BR-04023060 Sao Paulo, Brazil Univ Fed Sao Paulo Sao Paulo Brazil BR-04023060 BC3060 Sao Paulo, Brazil UNESP, Fac Odontol, Araraquara, Brazil UNESP Araraquara BrazilUNESP, Fac Odontol, Araraquara, Brazil
Titolo Testata:
HYPERTENSION
fascicolo: 4, volume: 34, anno: 1999,
parte:, 2 supplemento:, S
pagine: 739 - 743
SICI:
0194-911X(199910)34:4<739:CNLACR>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERIAL-PRESSURE; CONSCIOUS RATS; CAROTID OCCLUSION; BRAIN-STEM; NUCLEUS; PROJECTIONS;
Keywords:
blood pressure; baroreceptors; chemoreceptors; solitary nucleus; occlusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Colombari, E Univ Fed Sao Paulo, Escola Paulista Med, Dept Physiol, Rua Botucatu 862, BR-04023060 Sao Paulo, Brazil Univ Fed Sao Paulo Rua Botucatu 862 Sao Paulo Brazil BR-04023060 BC
Citazione:
M.A. Sato et al., "Commissural NTS lesions and cardiovascular responses in aortic baroreceptor-denervated rats", HYPERTENSIO, 34(4), 1999, pp. 739-743

Abstract

Both acute (1 day) lesions of the commissural nucleus of the solitary tract (commNTS) and aortic baroreceptor denervation increase presser responses to bilateral common carotid occlusion (BCO) during a 60-second period in conscious rats. In this study, we investigated the following: (1) the effectsof commNTS lesions on basal mean arterial pressure (MAP) and heart rate (HR) of aortic denervated (ADNx) rats; (2) the effects of acute commNTS lesions on presser responses to BCO in ADNx rats; and (3) the effects of chronic(10 days) commNTS lesions on the presser response to BCO, ADNx increased basal MAP and HR in sham-lesioned rats. Acute commNTS lesions abolished the MAP and HR increases observed in ADNx rats. Acute commNTS lesions increasedthe presser responses to BCO in rats with intact-baroreceptor innervation but produced no additional change in the presser response to BCO in ADNx rats. Chronic commNTS lesions did not change the presser responses to BCO in rats with intact-baroreceptor innervation. The data shaw that acute commNTSlesions abolish the MAP increase produced by aortic baroreceptor denervation. They also suggest that acute commNTS lesions enhance the presser response to BCO by partial withdrawal of aortic baroreceptor inputs into the NTS. Chronically, reorganization in the remaining aortic baroreceptor or in thebaroreflex function as a whole might produce normalization of the cardiovascular responses to BCO.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:06:52