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Titolo:
White-matter change in mesial temporal sclerosis: Correlation of MRI with PET, pathology, and clinical features
Autore:
Choi, D; Na, DG; Byun, HS; Suh, YL; Kim, SE; Ro, DW; Chung, IG; Hong, SC; Hong, SB;
Indirizzi:
Sung Kyun Kwan Univ, Sch Med, Dept Radiol, Samsung Med Ctr,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea Sung Kyun Kwan Univ, Sch Med, Dept Diagnost Pathol, Samsung Med Ctr,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea Sung Kyun Kwan Univ, Sch Med, Dept Nucl Med, Samsung Med Ctr,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea Sung Kyun Kwan Univ, Sch Med, Dept Neurosurg, Samsung Med Ctr,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea Sung Kyun Kwan Univ, Sch Med, Dept Neurol, Samsung Med Ctr,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea
Titolo Testata:
EPILEPSIA
fascicolo: 11, volume: 40, anno: 1999,
pagine: 1634 - 1641
SICI:
0013-9580(199911)40:11<1634:WCIMTS>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; LOBE EPILEPSY; HIPPOCAMPAL SCLEROSIS; LOBECTOMY; SEIZURES; HYPOMETABOLISM; DIAGNOSIS; CT;
Keywords:
mesial temporal sclerosis; epilepsy; magnetic resonance imaging; positron emission tomography; white matter change;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Byun, HS Sung Kyun Kwan Univ, Sch Med, Dept Radiol, Samsung Med Ctr,Kangnam Ku, 50 Ilwon Dong, Seoul 135710, South Korea Sung Kyun Kwan Univ 50 IlwonDong Seoul South Korea 135710 Korea
Citazione:
D. Choi et al., "White-matter change in mesial temporal sclerosis: Correlation of MRI with PET, pathology, and clinical features", EPILEPSIA, 40(11), 1999, pp. 1634-1641

Abstract

Purpose: To assess the magnetic resonance imaging (MRI), positron emissiontomography (PET), pathology, and clinical findings of patients with the MRI feature of white-matter change (WMC) in the anterior temporal lobe. Methods: Fifty-six patients with pathologically proven mesial temporal sclerosis were included in this study. MRI and F-18-2-deoxyglucose(FDG) PET images were obtained before surgery in all patients. The patients were divided into two groups according to the presence of WMC on their MRI. WMC consists of an indistinct gray-white matter demarcation and an increased signal intensity of the anterior temporal lobe on T-2- weighted images. The two groups were then compared in terms of MRI, PET, pathology, and clinical features. Results: The MRI feature of WMC was observed in 18(32%) of the 56 patients. PET images of those patients revealed more severe hypometabolism of the ipsilateral temporal lobes (p < 0.05). In terms of histologic findings, larger numbers of heterotopic neurons were observed in the anterior temporal lobe white matter of these patients who also shared the following clinical features: earlier seizure onset, frequent history of febrile convulsions, andfavorable surgical outcomes. Conclusions: The MRI feature of WMC is an additive sign for correct seizure lateralization and may be related to a favorable surgical outcome in patients with temporal lobe epilepsy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/06/20 alle ore 02:25:39