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Titolo:
Epithelioid angiosarcoma associated with a Dacron vascular graft
Autore:
Ben-Izhak, O; Vlodavsky, E; Ofer, A; Engel, A; Nitecky, S; Hoffman, A;
Indirizzi:
Technion Israel Inst Technol, Rambam Med Ctr, Dept Pathol, IL-31096 Haifa,Israel Technion Israel Inst Technol Haifa Israel IL-31096 IL-31096 Haifa,Israel Technion Israel Inst Technol, Rambam Med Ctr, Dept Imaging, IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 L-31096 Haifa, Israel Technion Israel Inst Technol, Rambam Med Ctr, Dept Vasc Surg, IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 L-31096 Haifa, Israel Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 L-31096 Haifa, Israel
Titolo Testata:
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
fascicolo: 11, volume: 23, anno: 1999,
pagine: 1418 - 1422
SICI:
0147-5185(199911)23:11<1418:EAAWAD>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOREIGN-BODY; PROSTHESIS; TUMORIGENESIS; SARCOMA; SITE;
Keywords:
angiosarcoma; foreign body; Dacron graft;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Ben-Izhak, O Technion Israel Inst Technol, Rambam Med Ctr, Dept Pathol, POB 9602, IL-31096 Haifa, Israel Technion Israel Inst Technol POB 9602 HaifaIsrael IL-31096
Citazione:
O. Ben-Izhak et al., "Epithelioid angiosarcoma associated with a Dacron vascular graft", AM J SURG P, 23(11), 1999, pp. 1418-1422

Abstract

Angiosarcoma developed at the site of a Dacron vascular prosthesis 8 yearsafter an aortobifemoral bypass graft insertion. The tumor was composed of epithelioid cells, which showed positive staining for cytokeratin and expression of the common endothelial markers CD31, CD34, and von Willebrand factor. Ultrastructural examination showed aggregates of large cells with intercellular lumina and focal perinuclear whorls of intermediate filaments, Thepatient, who had abdominal pain and weight loss, died of disseminated pelvic and abdominal disease 6 months after diagnosis. Sarcomas associated withvascular Dacron grafts and angiosarcomas associated with metal or polymer foreign bodies are rare. Their development is probably analogous to the common experimental development of foreign body-associated sarcomas in rodents. Physicians caring for patients with vascular grafts or metal foreign bodies should be aware of this complication.

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Documento generato il 20/01/21 alle ore 01:52:24