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Titolo:
Tutorial in biostatistics genetic mapping of complex traits
Autore:
Olson, JM; Witte, JS; Elston, RC;
Indirizzi:
Case Western Reserve Univ, Rammelkamp Ctr Educ & Res, Dept Epidemiol & Biostat, Cleveland, OH 44109 USA Case Western Reserve Univ Cleveland OH USA 44109 Cleveland, OH 44109 USA
Titolo Testata:
STATISTICS IN MEDICINE
fascicolo: 21, volume: 18, anno: 1999,
pagine: 2961 - 2981
SICI:
0277-6715(19991115)18:21<2961:TIBGMO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
DISCORDANT SIB PAIRS; LINKAGE DISEQUILIBRIUM; QUANTITATIVE-TRAIT; RECOMBINATION FRACTION; NUCLEAR FAMILIES; RELATIVE PAIRS; MARKER LOCI; LOD SCORES; TESTS; POPULATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
78
Recensione:
Indirizzi per estratti:
Indirizzo: Olson, JM Case Western Reserve Univ, Rammelkamp Ctr Educ & Res, Dept Epidemiol & Biostat, 2500 MetroHlth Dr,MetroHlth Campus, Cleveland, OH 44109 USACase Western Reserve Univ 2500 MetroHlth Dr,MetroHlth Campus Cleveland OH USA 44109
Citazione:
J.M. Olson et al., "Tutorial in biostatistics genetic mapping of complex traits", STAT MED, 18(21), 1999, pp. 2961-2981

Abstract

Statistical genetic mapping methods are powerful tools for finding genes that contribute to complex human traits. Mapping methods combine knowledge of the biological mechanisms of inheritance and the randomness inherent in those mechanisms to locate, with increasing precision, trait genes on the human genome. We provide an overview of the two major classes of mapping methods, genetic linkage analysis and linkage disequilibrium analysis, and related concepts of genetic inheritance. Copyright (C) 1999 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:02:13