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Titolo:
Dysembryoplastic neuroepithelial tumors. Features in eight cases, including two with unusual locations.
Autore:
Guesmi, H; Houtteville, JP; Courtheoux, P; Derlon, JM; Chapon, F;
Indirizzi:
CHRU Cote Nacre, Neuropathol Lab, F-14033 Caen, France CHRU Cote Nacre Caen France F-14033 europathol Lab, F-14033 Caen, France CHRU Cote Nacre, Serv Neurochirurg, F-14033 Caen, France CHRU Cote Nacre Caen France F-14033 v Neurochirurg, F-14033 Caen, France CHRU Cote Nacre, Serv Neuroradiol, F-14033 Caen, France CHRU Cote Nacre Caen France F-14033 rv Neuroradiol, F-14033 Caen, France
Titolo Testata:
NEUROCHIRURGIE
fascicolo: 3, volume: 45, anno: 1999,
pagine: 190 - 200
SICI:
0028-3770(199909)45:3<190:DNTFIE>2.0.ZU;2-H
Fonte:
ISI
Lingua:
FRE
Soggetto:
CENTRAL NEUROCYTOMA; CORTICAL DYSPLASIA; EPILEPSY; GANGLIOGLIOMA; APPEARANCE; SEIZURES;
Keywords:
dysembryoplastic neuroepithelial tumor; epilepsy; caudate nucleus; fornix; septum;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Chapon, F CHRU Cote Nacre, Neuropathol Lab, F-14033 Caen, France CHRU CoteNacre Caen France F-14033 Lab, F-14033 Caen, France
Citazione:
H. Guesmi et al., "Dysembryoplastic neuroepithelial tumors. Features in eight cases, including two with unusual locations.", NEUROCHIRE, 45(3), 1999, pp. 190-200

Abstract

Objectives. - Dysembryoplastic neuroepithelial tumors (DNTs) are usually located within the supratentorial cortex. We present a series of eight casesof DNTs including two cases with an extracortical location, one in the caudate nucleus, the other one expanded in the lateral ventricule, septum and fornix. An origin from secondary germinal layers, as previously suggested, can explain these extracortical locations. Material and methods. - Of the eight patients; seven had partial epilepticseizures es and one intracranial hypertension. All patients underwent clinical examination, a computed tomographic (CT) scan, a magnetic resonance imaging (MRI) and a surgical removal of the lesion with histological examination. Results. - Clinical examination was normal except in the case with intracranial hypertension where a bilateral papillary oedema was found In seven cases the CT scan showed a hypodense lesion of pseudocystic appearance. All lesions were hypointense on T2-weighted and hyperintense on T2-weighted MRI. Contrast enhancement was observed in two cases. The lesion was intracortical in six cases and extracortical in the remaining two : one in the head ofthe caudate nucleus and one in the trigo-noseptal region. Histological examination identified an appearance of DNT with a specific glioneuronal element in six cases. Conclusion. - The diagnosis of DNT can be suspected before histological examination on radiological features, chiefly because the tumor is located inthe supratentorial cortex. However, extracortical locations no exist, evenif unusual. As DNTs are always benign, knowledge and accurate diagnosis ofthese atypical cases are mandatory in order to avoid useless and even deleterious additional treatments, such as radiotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 02:56:01