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Titolo:
Genetic and antigenic diversity among eastern equine encephalitis viruses from North, Central, and South America
Autore:
Brault, AC; Powers, AM; Chavez, CLV; Lopez, RN; Cachon, MF; Gutierrez, LFL; Kang, WL; Tesh, RB; Shope, RE; Weaver, SC;
Indirizzi:
Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 h, Dept Pathol, Galveston, TX 77555 USA Univ Texas, Med Branch, Ctr Trop Dis, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 , Ctr Trop Dis, Galveston, TX 77555 USA Comis Mexico Estados Unidos Prevenc Fiebre Aftosa, Mexico City, DF, MexicoComis Mexico Estados Unidos Prevenc Fiebre Aftosa Mexico City DF Mexico Dispositivo Nacl Emergencia Sanidad Anim, Palo Alto, CA USA Dispositivo Nacl Emergencia Sanidad Anim Palo Alto CA USA o Alto, CA USA Dispositivo Nacl Emergencia Sanidad Anim, Tuxla, Mexico Dispositivo Nacl Emergencia Sanidad Anim Tuxla Mexico im, Tuxla, Mexico
Titolo Testata:
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
fascicolo: 4, volume: 61, anno: 1999,
pagine: 579 - 586
SICI:
0002-9637(199910)61:4<579:GAADAE>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENCEPHALOMYELITIS VIRUS; MOLECULAR EVOLUTION; ALPHAVIRUSES; IDENTIFICATION; SUBTYPE; STRAINS; COMPLEX; SWINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Weaver, SC Univ Texas, Med Branch, Dept Pathol, 301 Univ Blvd, Galveston, TX 77555 USA Univ Texas 301 Univ Blvd Galveston TX USA 77555 n, TX 77555 USA
Citazione:
A.C. Brault et al., "Genetic and antigenic diversity among eastern equine encephalitis viruses from North, Central, and South America", AM J TROP M, 61(4), 1999, pp. 579-586

Abstract

Eastern equine encephalitis virus (EEEV), the sole species in the EEE antigenic complex, is divided into North and South American antigenic varietiesbased on hemagglutination inhibition tests. Here we describe serologic andphylogenetic analyses of representatives of these varieties, spanning the entire temporal and geographic range available. Nucleotide sequencing and phylogenetic analyses revealed additional genetic diversity within the SouthAmerican variety; 3 major South/Central American lineages were identified including one represented by a single isolate from eastern Brazil, and 2 lineages with more widespread distributions in Central and South America. AllNorth American isolates comprised a single, highly conserved lineage with strains grouped by the time of isolation and to some extent by location. AnEEEV strain isolated during a 1996 equine outbreak in Tamaulipas State, Mexico was closely related to recent Texas isolates, suggesting southward EEEV transportation beyond the presumed enzootic range. Plaque reduction neutralization tests with representatives from the 4 major lineages indicated that each represents a distinct antigenic subtype. A taxonomic revision pf the EEE complex is proposed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 19:28:49