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Titolo:
Estrogen modulation of G-protein-coupled receptors
Autore:
Kelly, MJ; Wagner, EJ;
Indirizzi:
Oregon Hlth Sci Univ, Sch Med, Dept Physiol & Pharmacol, Portland, OR 97201 USA Oregon Hlth Sci Univ Portland OR USA 97201 rmacol, Portland, OR 97201 USA
Titolo Testata:
TRENDS IN ENDOCRINOLOGY AND METABOLISM
fascicolo: 9, volume: 10, anno: 1999,
pagine: 369 - 374
SICI:
1043-2760(199911)10:9<369:EMOGR>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
GONADOTROPIN-RELEASING-HORMONE; MESSENGER-RIBONUCLEIC-ACID; ENDOGENOUS OPIOID-PEPTIDES; ANTERIOR-PITUITARY GLAND; KAINATE-INDUCED CURRENTS; D2 DOPAMINE RECEPTOR; FEMALE RAT; GUINEA-PIG; KINASE-C; NEGATIVE FEEDBACK;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Kelly, MJ Oregon Hlth Sci Univ, Sch Med, Dept Physiol & Pharmacol, 3181 SWSam Jackson Pk,Mail Code 1334, Portland, OR 97201 USA Oregon Hlth Sci Univ3181 SW Sam Jackson Pk,Mail Code 1334 Portland OR USA 97201
Citazione:
M.J. Kelly e E.J. Wagner, "Estrogen modulation of G-protein-coupled receptors", TRENDS ENDO, 10(9), 1999, pp. 369-374

Abstract

Estrogen exerts long-term effects in almost every cell through regulation of gene transcription. However, it has been known for some time that estrogen can rapidly alter neuronal firing within seconds, indicating that some cellular effects of estrogen could occur via non-genomic mechanisms. G-protein-coupled receptors (GPCRs) are the largest class of membrane-bound receptors, and it appears that many of the rapid effects mediated by estrogen could involve changes in GPCR-effector system coupling in excitable cells within the reproductive axis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:37:00