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Titolo:
Nocturnal oximetry for the diagnosis of the sleep apnoea hypopnoea syndrome: a method to reduce the number of polysomnographies?
Autore:
Chiner, E; Signes-Costa, J; Arriero, JM; Marco, J; Fuentes, I; Sergado, A;
Indirizzi:
Univ San Juan Alicante Hosp, Secc Neurol, San Juan Alicante 03550, Spain Univ San Juan Alicante Hosp San Juan Alicante Spain 03550 e 03550, Spain
Titolo Testata:
THORAX
fascicolo: 11, volume: 54, anno: 1999,
pagine: 968 - 971
SICI:
0040-6376(199911)54:11<968:NOFTDO>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
HOME OXIMETRY; APNEA;
Keywords:
sleep apnoea hypopnoea syndrome; sleep apnoea syndrome; nocturnal oximetry; diagnosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Chiner, E Univ San Juan Alicante Hosp, Secc Neurol, Carretera Alicante Valencia S-N,San Juan Alicante 03550, Spain Univ San Juan Alicante Hosp Carretera Alicante Valencia S-N San Juan Alicante Spain 03550
Citazione:
E. Chiner et al., "Nocturnal oximetry for the diagnosis of the sleep apnoea hypopnoea syndrome: a method to reduce the number of polysomnographies?", THORAX, 54(11), 1999, pp. 968-971

Abstract

Background-Polysomnography (PSG) is currently the "gold standard" for the diagnosis of the sleep apnoea hypopnoea syndrome (SAHS). Nocturnal oximetry(NO) has been used with contradictory results. A prospective study was performed to determine the accuracy of NO as a diagnostic tool and to evaluatethe reduction in the number of PSGs if the diagnosis of SAHS had been established by this method. Methods-Two hundred and seventy five patients with a clinical suspicion ofSAHS were admitted to undergo, in the same night, full PSG and NO. Desaturation was defined as a fall in the haemoglobin saturation level (SaO(2)) tolower than 4% from the baseline level and an oxygen desaturation index perhour (ODI) was obtained in each patient with three cut off points: greaterthan or equal to 5 (ODI-5), greater than or equal to 10 (ODI-10), and greater than or equal to 15 (ODI-15). Results-SAHS was diagnosed in 216 patients (194 men). After withdrawing patients with abnormal lung function (forced expiratory volume in one second (FEV1) lower than 80% predicted), sensitivity (SE), specificity (SP), positive and negative predictive values (PPV and NPV) of NO were: ODI-5 (80%, 89%, 97%, 48%); ODI-10 (71%, 93%, 97%, 42%); ODI-15 (63%, 96%, 99%, 38%). Theaccuracy for each ODI was 0.81, 0.75, and 0.70, respectively. If NO had been considered as a diagnostic tool and PSG had been performed only in patients with a negative NO (false negative and true negative) and those with a positive NO and abnormal pulmonary function tests, 135/275 (ODI-5), 156/275(ODI-10), and 170/275 (ODI-15) PSGs would have been performed, a reductionof 140, 119, and 105, respectively. Conclusion-Nocturnal oximetry in patients with suspected SAHS and normal spirometric values permits the institution of therapeutic measures in most patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 19:11:00