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Titolo:
Antihypertensive therapy in renal patients - Benefits and difficulties
Autore:
Schwenger, V; Zeier, M; Ritz, E;
Indirizzi:
Univ Heidelberg Klinikum, Sekt Nephrol, D-69115 Heidelberg, Germany Univ Heidelberg Klinikum Heidelberg Germany D-69115 Heidelberg, Germany
Titolo Testata:
NEPHRON
fascicolo: 3, volume: 83, anno: 1999,
pagine: 202 - 213
SICI:
0028-2766(199911)83:3<202:ATIRP->2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE CONTROL; CONVERTING ENZYME-INHIBITION; DIABETIC NEPHROPATHY; MYOCARDIAL-INFARCTION; CARDIOVASCULAR OUTCOMES; DISEASE; PROGRESSION; FAILURE; HYPERTENSION; KIDNEY;
Keywords:
renal hypertension; renal failure, progression; proteinuria; angiotensin-converting enzyme inhibitors angiotensin receptor blockers; glomerular disease; antihypertensive treatment;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Schwenger, V Univ Heidelberg Klinikum, Sekt Nephrol, Bergheimer Str 56A, D-69115 Heidelberg, Germany Univ Heidelberg Klinikum Bergheimer Str 56A Heidelberg Germany D-69115
Citazione:
V. Schwenger et al., "Antihypertensive therapy in renal patients - Benefits and difficulties", NEPHRON, 83(3), 1999, pp. 202-213

Abstract

High blood pressure values, diastolic and systolic, are associated with decreased renal function. This is particularly true when the diastolic blood pressure is higher than 90 mm Hg. Several studies showed that lowering of the blood pressure within the range of normotension according to the WHO causes a reduction in the rate of progression to terminal renal failure. Thesestudies have led to recommendations to aim at a target blood pressure of approximately 125/75 mm Hg in the treatment of patients with glomerular diseases and particularly diabetic nephropathy with proteinuria >1 g/day. In contrast to these results, blood pressure values corresponding to the recommendation (less than or equal to 125/75 mm Hg) of the JNC VI (see text) were achieved in 15% of the patients only. It has also been shown that at any given level of an average 24-hour blood pressure, patients with an insufficient decrease of the blood pressure during nighttime have a higher risk to progress to terminal renal failure. Thus it is very important to lower the nighttime blood pressure and to detect nighttime blood pressure increases using ambulatory blood pressure measurements.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 12:21:58