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Titolo:
Lesions of periaqueductal gray dissociate-conditioned freezing from conditioned suppression behavior in rats
Autore:
Amorapanth, P; Nader, K; LeDoux, JE;
Indirizzi:
NYU, Ctr Neural Sci, New York, NY 10003 USA NYU New York NY USA 10003NYU, Ctr Neural Sci, New York, NY 10003 USA
Titolo Testata:
LEARNING & MEMORY
fascicolo: 5, volume: 6, anno: 1999,
pagine: 491 - 499
SICI:
1072-0502(199909/10)6:5<491:LOPGDF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL AMYGDALOID NUCLEUS; TEMPORAL CORTEX; FEAR; PROJECTIONS; ORGANIZATION; POTENTIATION; STIMULI; INVOLVEMENT; RESPONSES; STARTLE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Nader, K NYU, Ctr Neural Sci, New York, NY 10003 USA NYU New York NY USA 10003 Ctr Neural Sci, New York, NY 10003 USA
Citazione:
P. Amorapanth et al., "Lesions of periaqueductal gray dissociate-conditioned freezing from conditioned suppression behavior in rats", LEARN MEM, 6(5), 1999, pp. 491-499

Abstract

It is commonly assumed that suppression of an ongoing behavior is an indirect measure of freezing behavior. We tested whether conditioned suppressionand freezing are the same or distinct conditioned responses. Rats were trained to press a bar for food and then given fear-conditioning sessions in which a tone was paired with a foot shock (two pairings a day for 2 days). They then received either sham or electrolytic lesions of the periaqueductalgray (PAG). Post-training PAG lesions blocked freezing to the conditioned stimulus (CS), but had no effect on the suppression of operant behavior to the same CS. Thus, conditioned suppression and freezing, which both cause acessation in activity, appear to be mediated by separate processes.

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Documento generato il 07/07/20 alle ore 21:48:25