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Titolo:
Polyunsaturated fatty acids in human milk and their role in early infant development
Autore:
Koletzko, B; Rodriguez-Palmero, M;
Indirizzi:
Univ Munich, Dr Von Haunerschen Kinderspital, Div Metab Dis & Nutr, Kinderklin & Kinderpoliklin, D-80337 Munich, Germany Univ Munich Munich GermanyD-80337 nderpoliklin, D-80337 Munich, Germany
Titolo Testata:
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
fascicolo: 3, volume: 4, anno: 1999,
pagine: 269 - 284
SICI:
1083-3021(199907)4:3<269:PFAIHM>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
VISUAL-ACUITY DEVELOPMENT; SALT-STIMULATED LIPASE; BIRTH-WEIGHT INFANTS; FULL-TERM INFANTS; MATURE HUMAN-MILK; BREAST-MILK; PRETERM INFANTS; ARACHIDONIC-ACID; DOCOSAHEXAENOIC ACID; MARINE-OIL;
Keywords:
human milk; essential fatty acids; long-chain polyunsaturated fatty acids; arachidonic acid; docosahexaenoic acid; infant nutrition; infant development;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
106
Recensione:
Indirizzi per estratti:
Indirizzo: Koletzko, B Univ Munich, Dr Von Haunerschen Kinderspital, Div Metab Dis & Nutr, Kinderklin & Kinderpoliklin, Lindwurmstr 4, D-80337 Munich, Germany Univ Munich Lindwurmstr 4 Munich Germany D-80337 ich, Germany
Citazione:
B. Koletzko e M. Rodriguez-Palmero, "Polyunsaturated fatty acids in human milk and their role in early infant development", J MAMMARY G, 4(3), 1999, pp. 269-284

Abstract

The lipid fraction of human milk represents the main source of energy for the newborn infant and supplies essential nutrients such as fat-soluble vitamins and polyunsaturated fatty acids (PUFA).(3) The essential fatty acids linoleic and alpha-linolenic acids are precursors of long-chain polyunsaturated fatty acids (LC-PUFA), such as arachidonic (C20:4 n-6) and docosahexaenoic (C22:6 n-3) acids, present in human milk in considerable amounts. LC-PUFA are indispensable structural components of all cellular membranes, and they are incorporated in relatively large amounts during early growth of the brain and the retina. Moreover, some LC-PUFA are precursors of eicosanoids, molecules with potent biological activity that modulates various cellular and tissue processes. The supply of long-chain fatty acids has been associated with functional outcomes of the recipient infants such as visual acuity and development of cognitive functions during the first year of life. Here we discuss the PUFA composition of human milk, factors which determine and modulate milk PUFA content, and possible effects of milk LC-PUFA on infant growth and development.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 10:18:31