Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Visceral adiposity and incident coronary heart disease in Japanese-American men - The 10-year follow-up results of the Seattle Japanese-American Community Diabetes Study
Autore:
Fujimoto, WY; Bergstrom, RW; Boyko, EJ; Chen, KW; Leonetti, DL; Newell-Morris, L; Shofer, JB; Wahl, PW;
Indirizzi:
Univ Washington, Dept Med, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 ton, Dept Med, Seattle, WA 98195 USA Univ Washington, Dept Anthropol, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 ept Anthropol, Seattle, WA 98195 USA Univ Washington, Dept Biostat, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Dept Biostat, Seattle, WA 98195 USA
Titolo Testata:
DIABETES CARE
fascicolo: 11, volume: 22, anno: 1999,
pagine: 1808 - 1812
SICI:
0149-5992(199911)22:11<1808:VAAICH>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENSITY-LIPOPROTEIN PARTICLES; IMPAIRED GLUCOSE-TOLERANCE; BODY-FAT DISTRIBUTION; MIDDLE-AGED MEN; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; RISK-FACTORS; ACUTE HYPERGLYCEMIA; TISSUE DISTRIBUTION; HELSINKI POLICEMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Fujimoto, WY Univ Washington, Dept Med, Box 356426, Seattle, WA 98195 USA Univ Washington Box 356426 Seattle WA USA 98195 WA 98195 USA
Citazione:
W.Y. Fujimoto et al., "Visceral adiposity and incident coronary heart disease in Japanese-American men - The 10-year follow-up results of the Seattle Japanese-American Community Diabetes Study", DIABET CARE, 22(11), 1999, pp. 1808-1812

Abstract

OBJECTIVE - To identify risk factors for incident coronary: heart disease (CHD). RESEARCH DESIGN AND METHODS - A total of 175 Japanese-American men withoutCHD were followed for up to 10 years. Baseline variables were blood pressure, weight, BMI, fat areas by computed tomography, skinfold thicknesses, abdominal circumference, plasma insulin, C-peptide, cholesterol, LDL cholesterol, I-IDL cholesterol, HDL2 cholesterol, and HDL3 cholesterol, triglycerides, apoproteins AI and B, and diagnosis of diabetes and hypertension. CHD was diagnosed by electrocardiogram and clinical events. Logistic regression was used to estimate odds ratio. RESULTS - There were 50 incident cases of CHD. Using univariate logistic regression analysis, significant risk factors were intra-abdominal fat (P = 0.0090), fasting glucose (P = 0.0002), 2-h glucose (P = 0.0008), fasting HDL cholesterol (P = 0.0086), fasting HDL2 cholesterol (P = 0.030), fasting HDL3 cholesterol (P = 0.018), fasting triglycerides (P = 0.013), systolic (P= 0.0007) and diastolic blood pressure (P = 0.0002), and presence of diabetes (P = 0.0002). Multiple logistic regression models adjusted for BMI and age showed that intra-abdominar fat accounted for the effects of HDL cholesterol or triglycerides. In a multiple logistic regression model that included inh-a-abdominal fat, all systolic blood pressure and fasting glucose were significant. Substituting diastolic blood pressure for systolic blood pressure and 2-h glucose or diabetes status for fasting glucose produced similar results. CONCLUSIONS - Visceral adiposity blood pressure, and plasma glucose are important independent risk factors for incident CHD in this population of diabetic and nondiabetic Japanese-American men.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:46:49