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Titolo:
Mitochondrial transport of cations: Channels, exchangers, and permeabilitytransition
Autore:
Bernardi, P;
Indirizzi:
Univ Padua, Dept Biomed Sci, Padua, Italy Univ Padua Padua ItalyUniv Padua, Dept Biomed Sci, Padua, Italy CNR, Ctr Study Biomembranes, Padua, Italy CNR Padua ItalyCNR, Ctr Study Biomembranes, Padua, Italy
Titolo Testata:
PHYSIOLOGICAL REVIEWS
fascicolo: 4, volume: 79, anno: 1999,
pagine: 1127 - 1155
SICI:
0031-9333(199910)79:4<1127:MTOCCE>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT-LIVER MITOCHONDRIA; ADENINE-NUCLEOTIDE TRANSLOCASE; CALCIUM-ION TRANSPORT; OXIDATION-REDUCTION STATE; BEEF-HEART MITOCHONDRIA; K-ATP CHANNEL; CA-2+-INDUCED MEMBRANE TRANSITION; PROTON ELECTROCHEMICAL GRADIENT; PYRUVATE-DEHYDROGENASE ACTIVITY; TERT-BUTYL HYDROPEROXIDE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
369
Recensione:
Indirizzi per estratti:
Indirizzo: Bernardi, P Dipartimento Sci Biomed Sperimentali, Viale Giuseppe Colombo 3, I-35121 Padua, Italy Dipartimento Sci Biomed Sperimentali Viale Giuseppe Colombo 3 Padua Italy I-35121
Citazione:
P. Bernardi, "Mitochondrial transport of cations: Channels, exchangers, and permeabilitytransition", PHYSIOL REV, 79(4), 1999, pp. 1127-1155

Abstract

This review provides a selective history of how studies of mitochondrial cation transport (K+, Na+, Ca2+) developed in relation to the major themes of research in bioenergetics. It then covers in some detail specific transport pathways for these cations, and it introduces and discusses open problems about their nature and physiological function, particularly in relation to volume regulation and Ca2+ homeostasis. The review should provide the basic elements needed to understand both earlier mitochondrial literature and current problems associated with mitochondrial transport of cations and hopefully will foster new interest in the molecular definition of mitochondrial cation channels and exchangers as well as their roles in cell physiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 05:04:35