Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM
Autore:
Tominaga, S; Kuroiwa, K; Tago, K; Iwahana, H; Yanagisawa, K; Komatsu, N;
Indirizzi:
Jichi Med Sch, Dept Biochem, Minami Kawachi, Tochigi 3290498, Japan Jichi Med Sch Minami Kawachi Tochigi Japan 3290498 Tochigi 3290498, Japan Jichi Med Sch, Dept Med, Div Hematol, Minami Kawachi, Tochigi 3290498, Japan Jichi Med Sch Minami Kawachi Tochigi Japan 3290498 Tochigi 3290498, Japan Sci Univ Tokyo, Fac Sci & Technol, Dept Appl Biol Sci, Noda, Chiba 278, Japan Sci Univ Tokyo Noda Chiba Japan 278 Appl Biol Sci, Noda, Chiba 278, Japan
Titolo Testata:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
fascicolo: 1, volume: 264, anno: 1999,
pagine: 14 - 18
SICI:
0006-291X(19991014)264:1<14:PAEOAN>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; HELPER T-CELLS; INTERLEUKIN-1 RECEPTOR; RESPONSIVE GENE; GROWTH; ESTABLISHMENT; SEQUENCE; DNA; ERYTHROPOIETIN; SUBLINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Tominaga, S Jichi Med Sch, Dept Biochem, 3311-1 Yakushiji, Minami Kawachi,Tochigi 3290498, Japan Jichi Med Sch 3311-1 Yakushiji Minami Kawachi Tochigi Japan 3290498
Citazione:
S. Tominaga et al., "Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM", BIOC BIOP R, 264(1), 1999, pp. 14-18

Abstract

A novel variant cDNA from the human ST2 gene other than ST2 or ST2L was identified and tentatively named ST2V. Alternative splicing inserts a new exon which leads to a change in the C-terminal portion of ST2, causing it to gain a hydrophobic tail instead of losing the third immunoglobulin-like domain. ST2V is expressed in human leukemic cell line UT-7 and its sublines UT-7/GM, UT-7/EPO, and UT-7/TPO, in addition to human helper T cell line 5C10. The amount of ST2V mRNA is greatly diminished when UT-7/GM cells are induced to differentiate into either erythroblastic or megakaryoblastic phenotypes. The possible roles of the ST2V in growth and differentiation are intriguing. (C) 1999 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 00:46:41