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Titolo:
Intestinal microsporidiosis occurring in two renal transplant recipients treated with mycophenolate mofetil
Autore:
Guerard, A; Rabodonirina, M; Cotte, L; Liguory, O; Piens, MA; Daoud, S; Picot, S; Touraine, JL;
Indirizzi:
Hop Edouard Herriot, Serv Parasitol Mycol Med & Malad Trop, F-69373 Lyon 08, France Hop Edouard Herriot Lyon France 08 & Malad Trop, F-69373 Lyon 08, France Hop Edouard Herriot, Serv Transplantat Renale & Immunol Clin, F-69373 Lyon, France Hop Edouard Herriot Lyon France F-69373 munol Clin, F-69373 Lyon, France Hop Hotel Dieu, Serv Hepatogastroenterol & Sidol, Lyon, France Hop Hotel Dieu Lyon France rv Hepatogastroenterol & Sidol, Lyon, France Hop St Louis, Clin Malad Infectieuses & Trop, Paris, France Hop St Louis Paris France Clin Malad Infectieuses & Trop, Paris, France
Titolo Testata:
TRANSPLANTATION
fascicolo: 5, volume: 68, anno: 1999,
pagine: 699 - 701
SICI:
0041-1337(19990915)68:5<699:IMOITR>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTEROCYTOZOON-BIENEUSI; INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Rabodonirina, M Hop Edouard Herriot, Serv Parasitol Mycol Med & Malad Trop, Domaine Rockefeller,8 Ave Rockefeller, F-69373 Lyon 08, France Hop Edouard Herriot Domaine Rockefeller,8 Ave Rockefeller Lyon France 08
Citazione:
A. Guerard et al., "Intestinal microsporidiosis occurring in two renal transplant recipients treated with mycophenolate mofetil", TRANSPLANT, 68(5), 1999, pp. 699-701

Abstract

Background. Intestinal microsporidiosis is a major cause of chronic diarrhea and malabsorption in patients with human immunodeficiency virus. Its occurrence in transplant recipients has exceptionally been reported to date. Methods. We report what we believe are the first two cases of intestinal microsporidiosis in renal transplant recipients. The patients were treated with mycophenolate mofetil. Results. The clinical presentation was chronic diarrhea with massive weight loss. Stool analysis revealed microsporidian spores, identified as Enterocytozoon bieneusi spores by polymerase chain reaction. The onset of this opportunistic infection in these two patients is believed to be secondary to an increase in immunosuppression after azathioprine replacement by mycophenolate mofetil. The withdrawal of mycophenolate mofetil led to clinical recovery. Conclusion. The incidence of microsporidiosis will probably increase in transplant recipients treated with powerful immunosuppressants. Therefore, werecommend a systematic search for microsporidian spores in stool specimensin cases of unexplained diarrhea in these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 19:44:03