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Titolo:
Clinical features and treatment interventions for human immunodeficiency virus-associated neurologic disease in children
Autore:
Mintz, M;
Indirizzi:
Childrens Hosp Philadelphia, Dept Neurol, Philadelphia, PA USA Childrens Hosp Philadelphia Philadelphia PA USA ol, Philadelphia, PA USA Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA Childrens Hosp Philadelphia Philadelphia PA USA 19104 lphia, PA 19104 USA
Titolo Testata:
SEMINARS IN NEUROLOGY
fascicolo: 2, volume: 19, anno: 1999,
pagine: 165 - 176
SICI:
0271-8235(1999)19:2<165:CFATIF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPTOMATIC HIV DISEASE; CENTRAL-NERVOUS-SYSTEM; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; TERM ZIDOVUDINE THERAPY; AIDS DEMENTIA COMPLEX; TUMOR-NECROSIS-FACTOR; CEREBROSPINAL-FLUID; INFECTED CHILDREN; TYPE-1 INFECTION; HIV-1-INFECTED CHILDREN;
Keywords:
human immunodeficiency virus type-1; HIV; acquired immunodeficiency syndrome; AIDS; progressive encephalopathy; pediatric; children; neurologic disease; opportunistic infection; neurobehavioral; psychiatric;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
110
Recensione:
Indirizzi per estratti:
Indirizzo: Mintz, M Childrens Hosp Philadelphia, Specialty Ctr, 1012 Laurel Oak Rd, Voorhees, NJ 08043 USA Childrens Hosp Philadelphia 1012 Laurel Oak Rd Voorhees NJ USA 08043
Citazione:
M. Mintz, "Clinical features and treatment interventions for human immunodeficiency virus-associated neurologic disease in children", SEM NEUROL, 19(2), 1999, pp. 165-176

Abstract

HIV-1 infection in children and adolescents can cause progressive neurologic disease, affective brain growth, motor function, and neurodevelopment, In addition, myelopathies, neuropathies, myopathies, strokes, and psychiatric or behavioral manifestations can be a result of HIV-1 infection, OI, or toxicities of treatment interventions. CNS OI are important causes of morbidity and mortality, often mimicking the HIV-1 associated neurologic syndromes. Psychometric, clinical, neuroradiologic, and laboratory testing are valuable for diagnostic and treatment decisions. The cornerstone of treating HIV-1-associated neurologic disease is providing an effective regimen of antiretroviral drugs to reduce the viral burden. It is also necessary to provide rehabilitation, optimize nutrition, supply appropriate antimicrobial prophylaxis against OI, minimize pain, and treat neurobehavioral or psychiatriccomplications. Efforts at preventing HIV-1 infection are important for diminishing and allaying the growth of this international pandemic.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 18:16:18