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Titolo:
Validation of a new noninvasive, method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve - Comparison with intracoronary Doppler flow wire
Autore:
Caiati, C; Montaldo, C; Zedda, N; Montisci, R; Ruscazio, V; Lai, G; Cadeddu, J; Meloni, L; Iliceto, S;
Indirizzi:
Univ Cagliari, Inst Cardiol, Cagliari, Italy Univ Cagliari Cagliari Italy iv Cagliari, Inst Cardiol, Cagliari, Italy S Maugeri Fdn, IRCCS Med Ctr Rehabil, Div Cardiol, Cassano Murge, Italy S Maugeri Fdn Cassano Murge Italy il, Div Cardiol, Cassano Murge, Italy
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
fascicolo: 4, volume: 34, anno: 1999,
pagine: 1193 - 1200
SICI:
0735-1097(199910)34:4<1193:VOANNM>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERY DISEASE; TRANSESOPHAGEAL; ADENOSINE; ECHOCARDIOGRAPHY; DIPYRIDAMOLE; VASODILATION; INJECTION; VELOCITY; AGENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Caiati, C Univ Cagliari, Osped S Giovanni di Dio, Cattedra & Div Cardiol, Via Osped 46, I-09124 Cagliari, Italy Univ Cagliari Via Osped 46 Cagliari Italy I-09124 gliari, Italy
Citazione:
C. Caiati et al., "Validation of a new noninvasive, method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve - Comparison with intracoronary Doppler flow wire", J AM COL C, 34(4), 1999, pp. 1193-1200

Abstract

OBJECTIVES We tested the hypothesis that coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD) as assessed by a new noninvasive method (contrast-enhanced transthoracic second harmonic echo Doppler) is in agreement with CFR measurements assessed by intracoronary Doppler flow wire. BACKGROUND Contrast-enhanced transthoracic second harmonic echo Doppler isa novel noninvasive method to detect blood flow velocity and reserve in the LAD. However, it has not yet been validated versus a gold-standard method. METHODS Twenty-five patients undergoing CFR assessment in the LAD by Doppler flow wire were also evaluated by contrast-enhanced transthoracic Dopplerto record blood flow in the distal LAD at rest and during hyperemia obtained by adenosine IV infusion. In five patients CFR was evaluated twice (before and after angioplasty). RESULTS As a result of the combined use of IV contrast and second harmonicDoppler technology, feasibility in assessing coronary flow reserve equaled100%. The agreement between the two methods was high. In fact, in all but five patients the maximum difference between the two CFR measurements was 0.38. Overall, the prediction (95%) interval of individual differences was -0.69 to +0.72. Reproducibility of CFR measurements was also high. The limits of the agreement (95%) between the two measurements were -0.32 to +0.32. CONCLUSIONS Coronary flow reserve in the LAD as assessed by contrast-enhanced transthoracic echo Doppler along with harmonic mode concurs very closely with Doppler flow wire CFR measurements. This new noninvasive method allows feasible, reliable and reproducible assessment of CFR in the LAD. (J Am Coll Cardiol 1999;34:1193-200) (C) 1999 by the American College of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 20:00:20