Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Early recovery of coronary flow reserve after stent implantation as assessed by positron emission tomography
Autore:
Kosa, I; Blasini, R; Schneider-Eicke, J; Dickfeld, T; Neumann, FJ; Ziegler, S; Matsunari, I; Neverve, J; Schomig, A; Schwaiger, M;
Indirizzi:
Tech Univ Munich, Klinikum Rechts Isar, Dept Nucl Med, D-81675 Munich, Germany Tech Univ Munich Munich Germany D-81675 ucl Med, D-81675 Munich, Germany Tech Univ Munich, Klinikum Rechts Isar, Dept Internal Med, D-81675 Munich,Germany Tech Univ Munich Munich Germany D-81675 rnal Med, D-81675 Munich,Germany
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
fascicolo: 4, volume: 34, anno: 1999,
pagine: 1036 - 1041
SICI:
0735-1097(199910)34:4<1036:EROCFR>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERIAL INTRAVASCULAR ULTRASOUND; MYOCARDIAL PERFUSION RESERVE; BLOOD-FLOW; ARTERY DISEASE; BALLOON ANGIOPLASTY; NONINVASIVE QUANTIFICATION; VASODILATOR RESERVE; N-13 AMMONIA; TIME-COURSE; RESTENOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Schwaiger, M Tech Univ Munich, Klinikum Rechts Isar, Dept Nucl Med, Ismaninger Str 22, D-81675 Munich, Germany Tech Univ Munich Ismaninger Str 22 Munich Germany D-81675 ny
Citazione:
I. Kosa et al., "Early recovery of coronary flow reserve after stent implantation as assessed by positron emission tomography", J AM COL C, 34(4), 1999, pp. 1036-1041

Abstract

OBJECTIVES The aim of this study was to quantitatively evaluate myocardialflow reserve in patients early after coronary stent implantation using positron emission tomography. BACKGROUND Delayed restoration of coronary flow reserve after percutaneoustransluminal corollary angioplasty (PTCA) has been observed using a variety of techniques. Altered distal vasoregulation as well as residual stenosishave been considered possible explanations for this phenomenon. Although the implantation of stents may influence some of these mechanisms, little data are available characterizing coronary flow reserve early after stent placement. METHODS In 14 patients 1.6 +/- 0.6 days after stenting, N-13-ammonia positron emission tomographic studies were performed at rest and during adenosine-induced vasodilation. Myocardial blood flow was quantified using a three-compartment model. Rest and stress flow data, as well as coronary flow reserve of stented vascular territories, were compared with that of remote areas. RESULTS The stenosis decreased from 72.1 +/- 7.3% to 3.7 +/- 6.7% after stent implantation. Coronary flow in the stented areas did not differ significantly from that in remote areas either at rest (76.1 +/- 18.5 and 75.7 +/-17.7 ml/min/100 g, respectively), or during maximal vasodilation (205.5 +/- 59.9 and 179.4 +/- 47.4 ml/min/100 g, respectively). In addition, there was no significant difference in the calculated values of coronary reserve of these two regions (2.74 +/- 0.64 and 2.43 +/- 0.55, respectively). CONCLUSIONS The mechanical support of dilated arteries by a stent not onlyrestores the macroscopic integrity of epicardial arteries, but also results, in contrast to conventional PTCA procedures, in early recovery of flow reserve. (J Am Cell Cardiol 1999;34:1036-41) (C) 1999 by the American College of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 01:20:06