Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Multimodal MR imaging: Functional, diffusion tensor, and chemical shift imaging in a patient with localization-related epilepsy
Autore:
Krakow, K; Wieshmann, UC; Woermann, FG; Symms, MR; McLean, MA; Lemieux, L; Allen, PJ; Barker, GJ; Fish, DR; Duncan, JS;
Indirizzi:
Chalfont Ctr, Natl Soc Epilepsy, MRI Unit, Gerrards Cross SL9 0RJ, Bucks, England Chalfont Ctr Gerrards Cross Bucks England SL9 0RJ SL9 0RJ, Bucks, England Univ Coll London, Inst Neurol, Dept Clin Neurol, Epilepsy Res Grp, London,England Univ Coll London London England eurol, Epilepsy Res Grp, London,England Natl Hosp Neurol & Neurosurg, Dept Clin Neurophysiol, London WC1N 3BG, England Natl Hosp Neurol & Neurosurg London England WC1N 3BG n WC1N 3BG, England UCL, Inst Neurol, Dept Clin Neurol, NMR Res Unit, London, England UCL London England rol, Dept Clin Neurol, NMR Res Unit, London, England
Titolo Testata:
EPILEPSIA
fascicolo: 10, volume: 40, anno: 1999,
pagine: 1459 - 1462
SICI:
0013-9580(199910)40:10<1459:MMIFDT>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
EEG; NORMALIZATION;
Keywords:
functional MRI; diffusion tensor imaging; chemical shift imaging; EEG; localization-related epilepsy; malformation of cortical development (MCD);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Krakow, K Chalfont Ctr, Natl Soc Epilepsy, MRI Unit, Gerrards Cross SL9 0RJ, Bucks, England Chalfont Ctr Gerrards Cross Bucks England SL9 0RJ ucks, England
Citazione:
K. Krakow et al., "Multimodal MR imaging: Functional, diffusion tensor, and chemical shift imaging in a patient with localization-related epilepsy", EPILEPSIA, 40(10), 1999, pp. 1459-1462

Abstract

Purpose: To demonstrate the integration of complementary functional and structural data acquired with magnetic resonance imaging (MRI) in a patient with localization-related epilepsy. Methods: We studied a patient with partial and secondarily generalized seizures and a hemiparesis due to a malformation of cortical development (MCD)in the right hemisphere by using EEG-triggered functional MRI (fMRI), diffusion tensor imaging (DTI), and chemical shift imaging (CSI). Results: fMRI revealed significant changes in regional blood oxygenation associated with interictal epileptiform discharges within the MCD. DTI showed a heterogeneous microstructure of the MCD with reduced fractional anisotropy, a high mean diffusivity, and displacement of myelinated tracts. CSI demonstrated low N-acetyl aspartate (NAA) concentrations in parts of the MCD. Conclusions: The applied MR methods described functional, microstructural,and biochemical characteristics of the epileptogenic tissue that cannot beobtained with other noninvasive means and thus improve the understanding of the pathophysiology of epilepsy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 10:21:44