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Titolo:
ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeletan
Autore:
Blake, KJ; Myette, G; Jack, J;
Indirizzi:
Univ Connecticut, Ctr Hlth, Dept Anat, Farmington, CT 06030 USA Univ Connecticut Farmington CT USA 06030 t Anat, Farmington, CT 06030 USA
Titolo Testata:
DEVELOPMENT GENES AND EVOLUTION
fascicolo: 9, volume: 209, anno: 1999,
pagine: 555 - 559
SICI:
0949-944X(199909)209:9<555:RRAZHD>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONMUSCLE MYOSIN; MORPHOGENESIS; MELANOGASTER; PROTEINS; SHAPE;
Keywords:
morphogenesis; cell shape; nonmuscle myosin; cytoskeleton;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Jack, J Univ Connecticut, Ctr Hlth, Dept Anat, MC 3405,263 Farmington Ave,Farmington, CT 06030 USA Univ Connecticut MC 3405,263 Farmington Ave Farmington CT USA 06030
Citazione:
K.J. Blake et al., "ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeletan", DEV GENES E, 209(9), 1999, pp. 555-559

Abstract

rib and raw mutations prevent cells in a number of tissues from assuming specialized shapes, resulting in abnormal tubular epithelia and failure of morphogenetic movements such as dorsal closure. Mutations of zip, which encodes the nonmuscle myosin heavy chain, suppress the phenotypes of rib and raw, suggesting that rib and raw are not directly required for myosin function. Abnormal formation of the actin cytoskeletal structures underlying embryonic cuticular hairs suggests possible roles for rib and raw in organizing the actin cytol skeleton. The actin prehair structures are absent in rib mutants and abnormally shaped in raw mutants, indicating that the two genes have different functions required for organizing the actin cytoskeleton.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 03:45:16