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Titolo:
Malignant pheochromocytoma in the 17th week of gestation
Autore:
Remmel, E; Oertli, D; Holzgreve, W; Hosli, I; Staub, JJ; Harder, F;
Indirizzi:
Univ Basel, Dept Chirurg, Chirurg Klin, CH-4003 Basel, Switzerland Univ Basel Basel Switzerland CH-4003 rg Klin, CH-4003 Basel, Switzerland Univ Basel, Abt Endokrinol, CH-4003 Basel, Switzerland Univ Basel Basel Switzerland CH-4003 okrinol, CH-4003 Basel, Switzerland
Titolo Testata:
CHIRURG
fascicolo: 9, volume: 70, anno: 1999,
pagine: 1053 - 1057
SICI:
0009-4722(199909)70:9<1053:MPIT1W>2.0.ZU;2-H
Fonte:
ISI
Lingua:
GER
Soggetto:
PREGNANCY; MANAGEMENT; DIAGNOSIS; PATIENT; TUMORS;
Keywords:
pheochromocytoma; pregnancy; metastatic pheochromocytoma; cancer in pregnancy; hypertension in pregnancy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Remmel, E Univ Klin Basel, Dept Chirurg, Spitalstr 21, CH-4031 Basel, Switzerland Univ Klin Basel Spitalstr 21 Basel Switzerland CH-4031 tzerland
Citazione:
E. Remmel et al., "Malignant pheochromocytoma in the 17th week of gestation", CHIRURG, 70(9), 1999, pp. 1053-1057

Abstract

Introduction: Pheochromocytoma during pregnancy is rare and represents a high risk for mother and fetus. Due to the variable clinical presentation itmay be mistaken for preeclampsia. Case: A 34-year-old primiapara with hypertension up to 240/120 mmHg. After diagnosis of a pheochromocytoma its resection together with lymph node metastasis in the 17th week of gestation wasperformed. Conclusion: The definitive diagnosis is confirmed by elevation of serum catecholamines and their metabolites in a 24-h urine collection. Localization during pregnancy can be made by ultrasound and MRI. The definitive treatment is surgical removal after administration of adrenergic blockers. If discovered later in pregnancy, delivery by elective caesarean section followed by tumor resection is recommended. Since about 10 % of pheochromocytomas are malignant, postpartum screening is required to detect and treat extraadrenal or metastatic tumors by MIBG scintigraphy, chemotherapy or surgical procedures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 05:13:10