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Titolo:
CHARACTERIZATION OF CEREBRAL BLOOD OXYGENATION AND FLOW CHANGES DURING PROLONGED BRAIN ACTIVATION
Autore:
BANDETTINI PA; KWONG KK; DAVIS TL; TOOTELL RBH; WONG EC; FOX PT; BELLIVEAU JW; WEISSKOFF RM; ROSEN BR;
Indirizzi:
MED COLL WISCONSIN,BIOPHYS RES INST,8701 W WATERTOWN PLANK RD MILWAUKEE WI 53226 MASSACHUSETTS GEN HOSP,DEPT RADIOL,NMR CTR CHARLESTOWN MA 00000 HARVARD UNIV,MIT,DIV HLTH SCI & TECHNOL CAMBRIDGE MA 02139 UNIV CALIF SAN DIEGO,DEPT RADIOL SAN DIEGO CA 92103 UNIV CALIF SAN DIEGO,DEPT PSYCHIAT SAN DIEGO CA 92103 UNIV TEXAS,HLTH SCI CTR SAN ANTONIO TX 00000
Titolo Testata:
Human brain mapping
fascicolo: 2, volume: 5, anno: 1997,
pagine: 93 - 109
SICI:
1065-9471(1997)5:2<93:COCBOA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN VISUAL-CORTEX; FUNCTIONAL MRI; SENSORY STIMULATION; PHOTIC-STIMULATION; INTRINSIC SIGNALS; CONTRAST; RESOLUTION; EPI; ARCHITECTURE; SPECTROSCOPY;
Keywords:
BOLD CONTRAST; FMRI; PET; DEOXYHEMOGLOBIN; NEURONAL HABITUATION; HUMAN BRAIN MAPPING; NEURONAL METABOLISM; BRAIN FUNCTION; PHOTIC STIMULATION; VISUAL CORTEX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
68
Recensione:
Indirizzi per estratti:
Citazione:
P.A. Bandettini et al., "CHARACTERIZATION OF CEREBRAL BLOOD OXYGENATION AND FLOW CHANGES DURING PROLONGED BRAIN ACTIVATION", Human brain mapping, 5(2), 1997, pp. 93-109

Abstract

The behavior of cerebral blood flow and oxygenation during prolonged brain activation was studied using magnetic resonance imaging (MRI) sensitized to flow and oxygenation changes, as well as positron emissiontomography sensitized to flow. Neuronal habituation effects and hemodynamic changes were evaluated across tasks and cortical regions. Nine types of activation stimuli or tasks, including motor activation, vibrotactile stimulation, and several types of visual stimulation, were used. Both flow and oxygenation were evaluated in separate time course series as well as simultaneously using two different MRI methods. In most cases, the activation-induced increase in flow and oxygenation remained elevated for the entire stimulation duration. These results suggest that both flow rate and oxygenation consumption rate remain constant during the entire time that primary cortical neurons are activated by a task or a stimulus. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:41:46