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Titolo:
Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein
Autore:
Slupska, MM; Luther, WM; Chiang, JH; Yang, HJ; Miller, JH;
Indirizzi:
Univ Calif Los Angeles, Dept Microbiol & Mol Genet, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
JOURNAL OF BACTERIOLOGY
fascicolo: 19, volume: 181, anno: 1999,
pagine: 6210 - 6213
SICI:
0021-9193(199910)181:19<6210:FEOHAH>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
METHYLPURINE-DNA GLYCOSYLASE; BASE EXCISION-REPAIR; G-A MISPAIRS; ENZYME; SYSTEM; GENE; TRANSVERSIONS; INTERMEDIATE; SUPERFAMILY; MUTATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Miller, JH Univ Calif Los Angeles, Dept Microbiol & Mol Genet, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 , CA 90095 USA
Citazione:
M.M. Slupska et al., "Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein", J BACT, 181(19), 1999, pp. 6210-6213

Abstract

We have previously described the hMYH cDNA and genomic clones (M. M. Slupska ct al., J. Bacteriol. 178:3885-3892, 1996). Here, vue report that the enzyme expressed from an hMYH cDNA clone in Escherichia coli complements the mutator phenotype in a mutY mutant and can remove A from an A 8-hydroxydeoxyguanine mismatch and to a lesser extent can remove A from an A.G mismatch in vitro.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/10/20 alle ore 05:54:30