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Titolo:
Superior temporal gyral volumes and laterality correlates of auditory hallucinations in schizophrenia
Autore:
Levitan, C; Ward, PB; Catts, SV;
Indirizzi:
Liverpool Hosp, Schizophrenia Res Unit, Liverpool, NSW 2170, Australia Liverpool Hosp Liverpool NSW Australia 2170 iverpool, NSW 2170, Australia Univ New S Wales, Sch Psychiat, Sydney, NSW, Australia Univ New S Wales Sydney NSW Australia h Psychiat, Sydney, NSW, Australia
Titolo Testata:
BIOLOGICAL PSYCHIATRY
fascicolo: 7, volume: 46, anno: 1999,
pagine: 955 - 962
SICI:
0006-3223(19991001)46:7<955:STGVAL>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR-BRAIN RATIO; THOUGHT-DISORDER; BLOOD-FLOW; SYMPTOMS; LOBE; ABNORMALITIES; RELIABILITY; ASYMMETRIES; MORPHOLOGY; DIAGNOSIS;
Keywords:
auditory hallucinations; schizophrenia; magnetic resonance imaging; superior temporal gyrus; laterality; language;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Ward, PB Liverpool Hosp, Schizophrenia Res Unit, Liverpool, NSW 2170, Australia Liverpool Hosp Liverpool NSW Australia 2170 NSW 2170, Australia
Citazione:
C. Levitan et al., "Superior temporal gyral volumes and laterality correlates of auditory hallucinations in schizophrenia", BIOL PSYCHI, 46(7), 1999, pp. 955-962

Abstract

Background: Previous studies have reported significant correlations, indicating an emerging relationship, between severity of auditory hallucinationsand reduced size of temporal lobe cortical regions implicated in language processing. The present study used high-resolution magnetic resonance imaging (MRI) scanning, along with assessment of functional lateralization via adichotic listening task (DLT), to extend these findings. Methods: Thirty patients with schizophrenia and a history of auditory hallucinations participated in the study. All were completely right-handed. Eleven subjects were currently hallucinating at the time of the study. Volumetric T1-weighted MRI scans were obtained and regions of interest were manually traced using the BRAINS package (Andreasen et al 1993). Whole brain, bilateral temporal lobe, and anterior superior temporal gyrus volumes were calculated. Subjects completed a binaural consonant-vowel DLT. Results: Increased severity of hallucinatory experience was significantly associated with smaller left anterior superior temporal gyrus volumes. Current hallucinators demonstrated a reduction in right ear advantage on the DLT. Conclusions: The results suggest that auditory hallucinations are subserved by a trait-like dysfunction in language-related neural networks, of whichthe superior temporal cortex forms one component. The findings are also consistent with theories proposing abnormal lateralization in the etiology ofauditory hallucinations. Biol Psychiatry 1999;46:955-962 (C) 1999 Society of Biological Psychiatry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:01:27