Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Muscle ATP synthesis and utilisation, balanced during flow-induced increase of respiration
Autore:
Janovska, A; Mejsnar, JA; Stefl, B;
Indirizzi:
Charles Univ, Fac Sci, Dept Physiol & Dev Biol, Prague 12800 2, Czech Republic Charles Univ Prague Czech Republic 12800 2 rague 12800 2, Czech Republic
Titolo Testata:
MOLECULAR AND CELLULAR BIOCHEMISTRY
fascicolo: 1-2, volume: 197, anno: 1999,
pagine: 49 - 52
SICI:
0300-8177(199907)197:1-2<49:MASAUB>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
INVIVO; METABOLITES; HEART;
Keywords:
muscle; bioenergetics; respiration control; ATP-turnover; creatine charge;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Mejsnar, JA Charles Univ, Fac Sci, Dept Physiol & Dev Biol, Vinicna 7, Prague 12800 2,Czech Republic Charles Univ Vinicna 7 Prague Czech Republic 12800 2 Republic
Citazione:
A. Janovska et al., "Muscle ATP synthesis and utilisation, balanced during flow-induced increase of respiration", MOL C BIOCH, 197(1-2), 1999, pp. 49-52

Abstract

To investigate the control of cell energetic metabolism, creatine charge, ATP/ADP ratio and oxygen consumption (as indicators of an energetic status,the balance between ATP synthesis and degradation and the aerobic ATP turnover, respectively) were evaluated in the rat gracilis muscle, perfused-superfused in vitro. During the perfusion rate of 70 mu l/min the ATP/ADP ratio, as well as the creatine charge are kept at the in vivo level. With the decrease of the rate toward 54 mu l/min (of an abundant oxygen delivery), the values of both parameters are lower than levels in vivo. With the increase of the rate up to 100 mu l/min, both parameters are kept at the in vivo level, when respiration increases by 125%. The data demonstrate the 'unmatched' control of ATP utilisation and synthesis steady rates during the low perfusion rate; during the increasing steady ATP turnover following the increased perfusion rate, the two fluxes are strikingly 'matched', i.e. precisely balanced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/10/20 alle ore 09:24:53