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Titolo:
Biological performance of a three-dimensional fabric as artificial cartilage in the repair of large osteochondral defects in rabbit
Autore:
Hasegawa, M; Sudo, A; Shikinami, Y; Uchida, A;
Indirizzi:
Mie Univ, Fac Med, Dept Orthopaed Surg, Tsu, Mie 5148507, Japan Mie Univ Tsu Mie Japan 5148507 pt Orthopaed Surg, Tsu, Mie 5148507, Japan Takiron Co Ltd, Yasurtomi cho, Hyogo 6712421, Japan Takiron Co Ltd Yasurtomi cho Hyogo Japan 6712421 ho, Hyogo 6712421, Japan
Titolo Testata:
BIOMATERIALS
fascicolo: 20, volume: 20, anno: 1999,
pagine: 1969 - 1975
SICI:
0142-9612(199910)20:20<1969:BPOATF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTICULAR-CARTILAGE; PERIOSTEAL GRAFTS; GROWTH-FACTOR; KNEE; RECONSTRUCTION; BONE; COMPOSITE; IMPLANT; MATRIX; GLASS;
Keywords:
artificial cartilage; three-dimensional fabric; fibrous implant; cartilage repair; biocompatibility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Hasegawa, M Mie Univ, Fac Med, Dept Orthopaed Surg, 2-174 Edobashi, Tsu, Mie 5148507, Japan Mie Univ 2-174 Edobashi Tsu Mie Japan 5148507 e 5148507, Japan
Citazione:
M. Hasegawa et al., "Biological performance of a three-dimensional fabric as artificial cartilage in the repair of large osteochondral defects in rabbit", BIOMATERIAL, 20(20), 1999, pp. 1969-1975

Abstract

A new artificial cartilage [A three-dimensional fabric (3-DF) comprising ultra-high molecular weight polyethylene fiber with a triaxial three-dimensional structure and coated with hydroxyapatite] was used to repair large osteochondral defects in rabbit knees. The knees with the 3-DF implanted in the osteochondral defects were evaluated 2-24 weeks after the operation macroscopically and microscopically. The 3-DF coated with hydroxyapatite was fixed firmly to the subchondral bone with the newly formed bone into and around the 3-DF. Hyaline-like cartilage was formed to a certain extent on the surface of the 3-DF, and the surface damage of the patella opposed to the 3-DF was minimal. In addition, the 3-DF caused no adverse effects such as particle disease, infection or severe synovitis during the experimental period. Consequently, the 3-DF seems to have successful biocompatibility in this rabbit experiment. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/08/20 alle ore 11:14:13