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Titolo:
Leucopenia under butyrophenones - successful treatment of severe schizophrenic psychoses by giving benperidol intermittent every other day
Autore:
Grube, M; Kurzweg, A;
Indirizzi:
Klin Psychiat & Psychotherapie, Frankfurt, Germany Klin Psychiat & Psychotherapie Frankfurt Germany ie, Frankfurt, Germany
Titolo Testata:
NERVENARZT
fascicolo: 9, volume: 70, anno: 1999,
pagine: 838 - 841
SICI:
0028-2804(199909)70:9<838:LUB-ST>2.0.ZU;2-B
Fonte:
ISI
Lingua:
GER
Soggetto:
CLOZAPINE-INDUCED AGRANULOCYTOSIS; DRUG-INDUCED AGRANULOCYTOSIS; HUMAN-BRAIN; RECEPTORS; DOPAMINE; IMMUNE;
Keywords:
butyrophenones; haloperidol; benperidol; leucopenia; intervall therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Grube, M Stadt Kliniken Frankfurt am Main Hochst, Klin Psychiat & Psychotherapie, Gotenstr 6-8, D-65907 Frankfurt, Germany Stadt Kliniken Frankfurt am Main Hochst Gotenstr 6-8 Frankfurt Germany D-65907
Citazione:
M. Grube e A. Kurzweg, "Leucopenia under butyrophenones - successful treatment of severe schizophrenic psychoses by giving benperidol intermittent every other day", NERVENARZT, 70(9), 1999, pp. 838-841

Abstract

In the monotherapeutic treatment of an acute schizophrenic psychoses with butyrophenones (haloperidol and benperidol) we saw immediate leucopenic reactions when the medication was given every day. In literature the risk of butyrophenone-induced blood dyscrasias seems to be underestimated. Thereforewe decided to report this single case evaluation. When benperidol (short elimination - half life period) was given every other day ("intervall-therapy") the blood cell count of the leucocytes normalized. Furthermore, the amount of psychopathological abnormalities measured by the Brief Psychiatric Rating Scale decreased under this intermittent treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:29:58