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Titolo:
An outbreak due to Echovirus type 30 in a neonatal unit in France in 1997:usefulness of PCR diagnosis
Autore:
Chambon, M; Bailly, JL; Beguet, A; Henquell, C; Archimbaud, C; Gaulme, J; Labbe, A; Malpuech, G; Peigue-Lafeuille, H;
Indirizzi:
Ctr Hosp Univ, Dept Paediat, Clermont Ferrand, France Ctr Hosp Univ Clermont Ferrand France Paediat, Clermont Ferrand, France Ctr Hosp Univ, Dept Clin Virol, Clermont Ferrand, France Ctr Hosp Univ Clermont Ferrand France n Virol, Clermont Ferrand, France
Titolo Testata:
JOURNAL OF HOSPITAL INFECTION
fascicolo: 1, volume: 43, anno: 1999,
pagine: 63 - 68
SICI:
0195-6701(199909)43:1<63:AODTET>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ASEPTIC-MENINGITIS; INFECTION;
Keywords:
enterovirus; echovirus type 30; nosocomial infection; neonate; rapid diagnosis; PCR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Peigue-Lafeuille, H Fac Med, Serv Virol, 28 Pl Henri Dunant, F-63001 Clermont Ferrand, France Fac Med 28 Pl Henri Dunant Clermont Ferrand France F-63001
Citazione:
M. Chambon et al., "An outbreak due to Echovirus type 30 in a neonatal unit in France in 1997:usefulness of PCR diagnosis", J HOSP INF, 43(1), 1999, pp. 63-68

Abstract

Between February and August 1997, 53 patients with enterovirus meningitis were hospitalized in Clermont-Ferrand, France. All but one were children. Echovirus type 30 was involved in 70% of cases with identified serotype. Theoutbreak ceased on August 8. Two months later, a neonate was admitted to the neonatal unit with an echovirus type 30 meningitis thought to be acquired at delivery. Twenty days later a nosocomial outbreak of echovirus type 30involving five neonates occurred. Two of them presented with meningitis and two with febrile seizure; One was asymptomatic. The retrospective examination of the maternal sera in a neutralization test, using the index case strain as a source of antigen, showed that none of the neonates was passivelyimmunized before hospitalization, The use of genome detection in cerebrospinal fluid allowed rapid diagnosis and infection was contained by re-inforcing hygiene measures. Prospective examination of stools in the neonatal andpaediatric units showed no further occurrences of the disease. No sporadiccase was observed in the general population. Hence, nosocomial infections can occur a long time after an outbreak in the general population; rapid diagnosis With molecular tools is useful both for a definite diagnosis in patients already hospitalized, and to act as a rapid alert, even in intervals between seasonal outbreaks. (C) 1999 The Hospital infection Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 15:58:16