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Titolo:
CONSANGUINITY AND COMMON ADULT DISEASES IN ISRAELI ARAB COMMUNITIES
Autore:
JABER L; SHOHAT T; ROTTER JI; SHOHAT M;
Indirizzi:
RABIN MED CTR,DEPT MED GENET,BEILINSON CAMPUS IL-49100 PETAH TIQWA ISRAEL BEILINSON MED CTR,FELSENSTEIN MED RES CTR,DEPT MED GENET IL-49100 PETAH TIQWA ISRAEL TAIBE CHILDRENS MED CTR TAIBE ISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL CEDARS SINAI MED CTR,CTR MED GENET BIRTH DEFECTS LOS ANGELES CA 90048 UNIV CALIF LOS ANGELES LOS ANGELES CA 00000
Titolo Testata:
American journal of medical genetics
fascicolo: 4, volume: 70, anno: 1997,
pagine: 346 - 348
SICI:
0148-7299(1997)70:4<346:CACADI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
MATINGS;
Keywords:
CONSANGUINITY; DIABETES MELLITUS; BRONCHIAL ASTHMA; DUODENAL ULCER; MYOCARDIAL INFARCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
L. Jaber et al., "CONSANGUINITY AND COMMON ADULT DISEASES IN ISRAELI ARAB COMMUNITIES", American journal of medical genetics, 70(4), 1997, pp. 346-348

Abstract

Consanguinity has a deleterious effect with regard to congenital malformation and rare autosomal recessive diseases; however, little information exists on its role in multifactorial common adult morbidity. We investigated the effects of consanguinity on the prevalence of common diseases in adulthood, including diabetes mellitus, myocardial infarction, bronchial asthma, and duodenal ulcer. As part of a larger study investigating the inbreeding coefficient in the Israeli-Arab community,we distributed questionnaires to parents of 4,100 second-grade students in 158 randomly chosen schools. Among the 3,772 responders (92%), 34.8% of the students' fathers and 31% of their mothers were found to be born to consanguineous matings. There was no difference in the prevalence (males, females) between the offspring of consanguineous versus non-consanguineous matings for diabetes mellitus (consanguinity: 4.3%,1.5% vs. non-consanguinity: 2.9%, 1.6%) myocardial infarction (2.7%, 0.03% vs. 2.3%, 0.03%), bronchial asthma (2.4%, 2.0% vs. 3.7%, 2.3%), or duodenal ulcer (7.0%, 3.0% vs. 7.8%, 2.9%), respectively. The studysuggests that even in a population with a high rate of consanguinity,there is no significant increase in the prevalence of these common adult diseases. Am. J. Med. Genet. 70:346-348, 1997. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/10/20 alle ore 00:52:11