Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Control of centrosome reproduction: The right number at the right time
Autore:
Sluder, G; Hinchcliffe, EH;
Indirizzi:
Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01605 USA Univ Massachusetts Worcester MA USA 01605 l Biol, Worcester, MA 01605 USA
Titolo Testata:
BIOLOGY OF THE CELL
fascicolo: 6, volume: 91, anno: 1999,
pagine: 413 - 427
SICI:
0248-4900(199907)91:6<413:COCRTR>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
HAMSTER OVARY CELLS; LINKAGE GROUP-XIX; SEA-URCHIN EGGS; SPINDLE FORMATION; MITOTIC SPINDLE; BASAL BODIES; PROTEIN-KINASE; CHLAMYDOMONAS-REINHARDTII; DNA-SYNTHESIS; ANTIBODY MICROINJECTION;
Keywords:
centriole; centrosome; cell cycle; cell division; cyclin dependent kinase; duplication; mitosis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
92
Recensione:
Indirizzi per estratti:
Indirizzo: Sluder, G Univ Massachusetts, Sch Med, Dept Cell Biol, 377 Plantat St, Worcester, MA01605 USA Univ Massachusetts 377 Plantat St Worcester MA USA 01605 605 USA
Citazione:
G. Sluder e E.H. Hinchcliffe, "Control of centrosome reproduction: The right number at the right time", BIO CELL, 91(6), 1999, pp. 413-427

Abstract

It is of great importance for the cell to precisely coordinate the doubling of the interphase centrosome with nuclear events during the cell cycle and limit the number of centrosomes it contains at the onset of mitosis to two and only two. The penalties for mistakes are abnormal spindle assembly, inappropriate chromosome distribution, and consequently, genomic instability. We review the functional properties of the mechanisms that control when the centrosome duplicates in the cell cycle and the controls for centrosome copy number. We look to limits that are intrinsic to the centrosome itself and controls imposed by cell cycle linked changes in cytoplasmic conditions. Control of centrosome reproduction is exercised at both levels. (C) 1999 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 19:14:43