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Titolo:
THE RELATION OF CHRONIC DISEASES TO ALL-CAUSE MORTALITY RISK - THE 7 COUNTRIES STUDY
Autore:
MENOTTI A; BLACKBURN H; SECCARECCIA F; KROMHOUT D; NISSINEN A; ARAVANIS C; GIAMPAOLI S; MOHACEK I; NEDELJKOVIC S; TOSHIMA H;
Indirizzi:
VIA ADDA 87 I-00198 ROME ITALY UNIV MINNESOTA,SCH PUBL HLTH,DIV EPIDEMIOL MINNEAPOLIS MN 55455 IST SUPER SANITA,EPIDEMIOL & BIOSTAT LAB I-00161 ROME ITALY NATL INST PUBL HLTH & ENVIRONM,PUBL HLTH RES DIV NL-3720 BA BILTHOVENNETHERLANDS UNIV KUOPIO,DEPT COMMUNITY HLTH & GEN PRACTICE FIN-70211 KUOPIO FINLAND ATHENS MED CTR ATHENS GREECE UNIV ZAGREB ZAGREB 41000 CROATIA UNIV BELGRADE,MED CTR,INST CARDIOVASC DIS BELGRADE YUGOSLAVIA KURUME UNIV HOSP,MED CTR KURUME FUKUOKA JAPAN
Titolo Testata:
Annals of medicine
fascicolo: 2, volume: 29, anno: 1997,
pagine: 135 - 141
SICI:
0785-3890(1997)29:2<135:TROCDT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
7 COUNTRIES; 12 COHORTS; PREDICTION; STROKE; POPULATION; SURVIVAL; SYMPTOMS; AGE;
Keywords:
CHRONIC DISEASES; MORTALITY; PREVALENCE; PROGNOSIS; RISK RATIOS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
A. Menotti et al., "THE RELATION OF CHRONIC DISEASES TO ALL-CAUSE MORTALITY RISK - THE 7 COUNTRIES STUDY", Annals of medicine, 29(2), 1997, pp. 135-141

Abstract

The relation of chronic conditions on all-cause mortality in population samples was studied based on observations from the Seven Countries Study. The objective of this work was to study the risk of death during a 15-year follow-up of middle-aged men in relation to six chronic diseases. Fifteen cohorts of men aged 50-69, totalling 8122 subjects, were examined around 1970 in seven countries: Finland, The Netherlands, Italy Croatia (former Yugoslavia), Serbia (former Yugoslavia), Greece and Japan. Clinical diagnoses findings were made for coronary heart disease (CHD), 'other heart diseases' (OTH), peripheral arterial disease(PAD), stroke (STR), chronic obstructive pulmonary disease (COPD), and diabetes mellitus (DIAB). All-cause mortality was assessed in the subsequent 15 years. Death rates and relative risks were estimated from crude data, and in proportional hazards models after adjustment for age, systolic blood pressure and serum cholesterol level, cigarette smoking and body mass index. Large regional differences were found in the prevalence of the six conditions. Weak relations were found between population prevalence of each disease and population death rates for that disease. Among cohorts the relative risk of death in 15 years from any cause, adjusted for other risk factors, showed little variation among countries. Pooled relative risks, adjusted by the inverse of variance (with 95% CI) were: for CHD, 1.81 (1.60-2.06); for OTH, 1.47 (1.28-1.69); for PAD, 1.64 (1.39-1.93); for STR, 1.56 (1.23-1.98); for COPD,1.67 (1.48-1.88); and for DIAB, 1.75 (1.43-2.15). The smallest variability of prognosis among countries was found for CHD, OTH and DIAB; the largest for PAD, STR and COPD. Despite simple clinical diagnostic procedures and large differences in prevalence, the relation of established prevalent conditions to subsequent all-cause mortality is relatively uniform among countries and across these conditions, with a relative risk of dying in 15 years usually ranging between 1.5 and 2.0.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 21:43:31