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Titolo:
CEREBROSPINAL-FLUID CILIARY NEUROTROPHIC FACTOR IN NEUROLOGICAL PATIENTS
Autore:
MASSARO AR; SORANZO C; CARNEVALE A;
Indirizzi:
CATHOLIC UNIV SACRED HEART,SCH MED,NEUROL INST I-00168 ROME ITALY FIDIA ADV BIOPOLYMERS ABANO TERME ITALY
Titolo Testata:
European neurology
fascicolo: 4, volume: 37, anno: 1997,
pagine: 243 - 246
SICI:
0014-3022(1997)37:4<243:CCNFIN>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; MULTIPLE-SCLEROSIS; INTERLEUKIN-6 LEVELS; DISORDERS; INJURY; SERUM;
Keywords:
CILIARY NEUROTROPHIC FACTOR; CEREBROSPINAL FLUID; MULTIPLE SCLEROSIS; GUILLAIN-BARRE SYNDROME; CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
A.R. Massaro et al., "CEREBROSPINAL-FLUID CILIARY NEUROTROPHIC FACTOR IN NEUROLOGICAL PATIENTS", European neurology, 37(4), 1997, pp. 243-246

Abstract

We developed a double sandwich immunoassay for the dosage of ciliary neurotrophic factor (CNTF) in cerebrospinal fluid (CSF), The detectionlimit was 100 pg/ml. This assay was applied to human CSF samples from14 normal subjects, 26 patients with multiple sclerosis (MS), 17 withGuillain-Barre syndrome (GBS) or chronic inflammatory demyelinating polyneuropathy (CIDP), and 22 with tumours of the central nervous system (CNS) or leucaemic meningosis (LM), Samples from normal control subjects and from patients with tumours did not contain detectable CNTF, Only 2 patients with LM were positive, and all the patients with inflammatory diseases of the CNS and peripheral nervous system were positive, The MS group presented a mean value of 240 pg/ml CNTF and the GBS/CIDP group a value of 430 pg/ml.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 18:12:49