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Titolo:
Indirect effect of sciatic nerve injury on the epidermal thickness of plantar glabrous skin in rats
Autore:
Stankovic, N; Johansson, O; Oqvist, G; Hildebrand, C;
Indirizzi:
Linkoping Univ, Dept Biomed & Surg, Div Cell Biol, Fac Hlth Sci, SE-58185 Linkoping, Sweden Linkoping Univ Linkoping Sweden SE-58185 Sci, SE-58185 Linkoping, Sweden Linkoping Univ, Dept Biomed & Surg, Div Plast Surg Hand Surg & Burns, Fac Hlth Sci, SE-58185 Linkoping, Sweden Linkoping Univ Linkoping Sweden SE-58185 Sci, SE-58185 Linkoping, Sweden Karolinska Inst, Expt Dermatol Unit, Dept Neurosci, Stockholm, Sweden Karolinska Inst Stockholm Sweden Unit, Dept Neurosci, Stockholm, Sweden
Titolo Testata:
SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY
fascicolo: 3, volume: 33, anno: 1999,
pagine: 273 - 279
SICI:
0284-4311(199909)33:3<273:IEOSNI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
FUNCTIONAL PROJECTION; HAIRY SKIN; KERATINOCYTES; REGENERATION; DENERVATION; LESIONS; AXONS;
Keywords:
sciatic nerve injury; skin thickness; keratinocyte proliferation; light microscopy; autoradiography; H-3-thymidine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Stankovic, N Linkoping Univ, Dept Biomed & Surg, Div Cell Biol, Fac Hlth Sci, SE-58185 Linkoping, Sweden Linkoping Univ Linkoping Sweden SE-58185 Linkoping, Sweden
Citazione:
N. Stankovic et al., "Indirect effect of sciatic nerve injury on the epidermal thickness of plantar glabrous skin in rats", SC J PLAST, 33(3), 1999, pp. 273-279

Abstract

In patients with nerve injuries, the skin over the denervated part tends to atrophy. Few experimental studies have dealt with this issue. In this paper we examine the effects of nerve injury on the epidermis in plantar glabrous skin in rats. Analysis of paraffin sections showed that the epidermis becomes abnormally thin after sciatic neurotomy and suture or neurectomy, but not after nerve crush. Autoradiographic analysis showed a subnormal number of thymidine-labelled epidermal cells in plantar skin of rats subjected to sciatic neurectomy. However, after selective division of the sciatic footbranches, with preserved function of thigh and leg muscles, the number of labelled epidermal cells did not differ significantly between the side operated on and the control side. We conclude that the effect of sciatic nerve division on plantar skin in rats is caused by the motor deficiency in the foot rather than by deficient innervation of the skin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 02:01:39