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Titolo:
Natural experimental models: The global search for biomedical paradigms among traditional, modernizing, and modern populations
Autore:
Garruto, RM; Little, MA; James, GD; Brown, DE;
Indirizzi:
SUNY Binghamton, Dept Anthropol, Binghamton, NY 13902 USA SUNY BinghamtonBinghamton NY USA 13902 thropol, Binghamton, NY 13902 USA SUNY Binghamton, Dept Biol Sci, Binghamton, NY 13902 USA SUNY Binghamton Binghamton NY USA 13902 iol Sci, Binghamton, NY 13902 USA SUNY Binghamton, Decker Sch Nursing, Binghamton, NY 13902 USA SUNY Binghamton Binghamton NY USA 13902 Nursing, Binghamton, NY 13902 USA SUNY Binghamton, Inst Primary & Preventat Hlth Care, Binghamton, NY 13902 USA SUNY Binghamton Binghamton NY USA 13902 th Care, Binghamton, NY 13902 USA NIH, Bethesda, MD 20892 USA NIH Bethesda MD USA 20892NIH, Bethesda, MD 20892 USA Univ Hawaii, Dept Anthropol, Hilo, HI 96720 USA Univ Hawaii Hilo HI USA 96720 Hawaii, Dept Anthropol, Hilo, HI 96720 USA
Titolo Testata:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
fascicolo: 18, volume: 96, anno: 1999,
pagine: 10536 - 10543
SICI:
0027-8424(19990831)96:18<10536:NEMTGS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
NOMADIC TURKANA PASTORALISTS; CATECHOLAMINE EXCRETION RATES; WESTERN SAMOAN MEN; BLOOD-PRESSURE; VILIUISK ENCEPHALOMYELITIS; STRESS; GROWTH; WOMEN; LIFESTYLE; PACIFIC;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
104
Recensione:
Indirizzi per estratti:
Indirizzo: Garruto, RM SUNY Binghamton, Dept Anthropol, Sci 1,Room 11,POB 6000, Binghamton, NY 13902 USA SUNY Binghamton Sci 1,Room 11,POB 6000 Binghamton NY USA 13902
Citazione:
R.M. Garruto et al., "Natural experimental models: The global search for biomedical paradigms among traditional, modernizing, and modern populations", P NAS US, 96(18), 1999, pp. 10536-10543

Abstract

During the past four decades, biomedical scientists have slowly begun to recognize the unique opportunities for studying biomedical processes, disease etiology, and mechanisms of pathogenesis in populations with unusual genetic structures, physiological characteristics, focal endemic disease, or special circumstances. Such populations greatly extend our research capabilities and provide a natural laboratory for studying relationships among biobehavioral, genetic, and ecological processes that are involved in the development of disease. The models presented illustrate three different types of natural experiments: those occurring in traditionally living, modernizing, and modern populations. The examples are drawn from current research that involves population mechanisms of adaptation among East African Turkana pastoralists; a search for etiology and mechanisms of pathogenesis of an emerging disease among the Yakut people of Siberia; and psychosocial stress, hypertension, and cardiovascular disease in women working outside the home in New York City and among subpopulations in Hawaii. The models in general, andthe examples in specific, represent natural laboratories in which relatively small intrapopulation differences and large interpopulation differences can be used to evaluate health and disease outcomes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 04:37:23