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Titolo:
Signal transduction pathway for anterior-posterior development in Drosophila
Autore:
Baek, KH; Lee, KY;
Indirizzi:
Harvard Univ, Sch Med, Dana Farber Canc Inst, Div Pediat Oncol, Boston, MA02115 USA Harvard Univ Boston MA USA 02115 t, Div Pediat Oncol, Boston, MA02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Adult Oncol, Boston, MA02115 USA Harvard Univ Boston MA USA 02115 t, Dept Adult Oncol, Boston, MA02115 USA
Titolo Testata:
JOURNAL OF BIOMEDICAL SCIENCE
fascicolo: 5, volume: 6, anno: 1999,
pagine: 314 - 319
SICI:
1021-7770(199909/10)6:5<314:STPFAD>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR TYROSINE KINASE; NUCLEOTIDE EXCHANGE; ADAPTER PROTEIN; PLASMA-MEMBRANE; BICOID PROTEIN; RAF; EMBRYO; TORSO; ACTIVATION; SEVENLESS;
Keywords:
signal transduction; receptor tyrosine kinase; oncogene; Raf;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Baek, KH Harvard Univ, Sch Med, Dana Farber Canc Inst, Div Pediat Oncol, 44 Binney St, Boston, MA 02115 USA Harvard Univ 44 Binney St Boston MA USA 02115 oston, MA 02115 USA
Citazione:
K.H. Baek e K.Y. Lee, "Signal transduction pathway for anterior-posterior development in Drosophila", J BIOMED SC, 6(5), 1999, pp. 314-319

Abstract

In Drosophila, the establishment of embryonic polarity along the anterior-posterior axis of the egg is determined by the activity of maternal gene products that accumulate during oogenesis, Amongst these are the Bicoid, the Nanos, and the terminal class gene products, some of which are oncoproteinsinvolved in signal transduction for the formation of terminal structures in the embryo. Several signal transduction pathways have been described in Drosophila, and this review explores the potential of oncogene studies usingone of those pathways - the terminal class signal transduction pathway - to better understand the cellular mechanisms of proto-oncogenes that mediatecellular responses in vertebrates including humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 02:56:22