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Titolo:
Plasmalogens reduce the viscosity of a surfactant-like phospholipid monolayer
Autore:
Tolle, A; Meier, W; Greune, G; Rudiger, M; Hofmann, KP; Rustow, B;
Indirizzi:
Humboldt Univ, Hosp Pediat, Dept Neonatol, Univ Hosp Charity, D-10098 Berlin, Germany Humboldt Univ Berlin Germany D-10098 sp Charity, D-10098 Berlin, Germany Humboldt Univ, Klinikum Charite, Inst Med Phys & Biophys, D-10098 Berlin, Germany Humboldt Univ Berlin Germany D-10098 & Biophys, D-10098 Berlin, Germany
Titolo Testata:
CHEMISTRY AND PHYSICS OF LIPIDS
fascicolo: 1-2, volume: 100, anno: 1999,
pagine: 81 - 87
SICI:
0009-3084(199907)100:1-2<81:PRTVOA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
AIR-WATER-INTERFACE; FLUORESCENCE LIGHT-MICROSCOPY; MODEL PULMONARY SURFACTANT; PROTEINS SP-B; SPREAD MONOLAYERS; LUNG SURFACTANT; SCANNING FORCE; SP-C;
Keywords:
dipalmitoyl phosphatidylcholine; surface tension; surface viscosity; surfactant phospholipids;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Rustow, B Humboldt Univ, Hosp Pediat, Dept Neonatol, Univ Hosp Charity, Schumannstr 20-21, D-10098 Berlin, Germany Humboldt Univ Schumannstr 20-21 Berlin Germany D-10098 Germany
Citazione:
A. Tolle et al., "Plasmalogens reduce the viscosity of a surfactant-like phospholipid monolayer", CHEM PHYS L, 100(1-2), 1999, pp. 81-87

Abstract

In this study, plasmalogen-free and plasmalogen-containing phospholipid (PL) mixtures were investigated, using the Wilhelmy balance and an oscillating drop surfactometer (ODS). Plasmalogen-containing films showed very low viscosity at very low surface tension compared with plasmalogen-free films. Ten mol% plasmalogens reduced the surface tension of the surfactant-like PL film containing 70 mol% dipalmitoyl phosphatidylcholine (PtdCho) from 47.8 /- 0.9 to 25.7 +/- 0.8 mN/m. At these surface tensions the viscosity of the plasmalogen-containing monolayer was reduced by a factor of six. The viscosity of PL films that contain plasmalogens in the range of natural surfactant (2.5 mol%) was only half as high as plasmalogen-free PL films. These results suggest that monolayers of natural surfactant containing sufficient amounts of plasmalogens remain fluid in the final phase of expiration. Theseproperties of a surfactant monolayer can facilitate the formation of a film reservoir during expiration and the re-spread of that film material during inspiration without him fragmentation. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:23:48