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Titolo:
Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: The CARDIA study
Autore:
Flack, JM; Kvasnicka, JH; Gardin, JM; Gidding, SS; Manolio, TA; Jacobs, DR;
Indirizzi:
Wayne State Univ, Harper Hosp,Med Ctr, Sch Med,Cardiovasc Epidemiol & ClinApplicat Prog, Div Endocrinol Metab & Hypertens,Dept Internal Me, Detroit,MI 48201 USA Wayne State Univ Detroit MI USA 48201 t Internal Me, Detroit,MI 48201 USA John D Dingell Vet Adm Med Ctr, Detroit, MI USA John D Dingell Vet Adm MedCtr Detroit MI USA m Med Ctr, Detroit, MI USA St Josephs Hosp, St Paul, MN USA St Josephs Hosp St Paul MN USASt Josephs Hosp, St Paul, MN USA Univ Calif Irvine, Orange, CA 92668 USA Univ Calif Irvine Orange CA USA 92668 Calif Irvine, Orange, CA 92668 USA Northwestern Univ, Sch Med, Chicago, IL USA Northwestern Univ Chicago IL USA hwestern Univ, Sch Med, Chicago, IL USA NHLBI, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892NHLBI, Bethesda, MD 20892 USA Univ Minnesota, Sch Publ Hlth, Minneapolis, MN USA Univ Minnesota Minneapolis MN USA ta, Sch Publ Hlth, Minneapolis, MN USA
Titolo Testata:
AMERICAN HEART JOURNAL
fascicolo: 3, volume: 138, anno: 1999,
parte:, 1
pagine: 486 - 492
SICI:
0002-8703(199909)138:3<486:AAPCOM>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREVALENCE; DIAGNOSIS; CHILDREN; WOMEN; MEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Flack, JM Wayne State Univ, Harper Hosp,Med Ctr, Sch Med,Cardiovasc Epidemiol & ClinApplicat Prog, Div Endocrinol Metab & Hypertens,Dept Internal Me,3990 John Rd,1 WS, Detroit, MI 48201 USA Wayne State Univ 3990 John Rd,1 WS Detroit MI USA 48201 8201 USA
Citazione:
J.M. Flack et al., "Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: The CARDIA study", AM HEART J, 138(3), 1999, pp. 486-492

Abstract

Objective To describe the epidemiology of echocardiographic mitral valve prolapse (MVP) and its anthropometric, physiologic, and psychobehavioral correlates with a cross-sectional analysis at 4 urban clinical centers. Patients A biethnic, community-based sample of 4136 young (aged 23 to 35 years) adult participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study who had echocardiograms during their third examinationbetween 1990 and 1991. Measurements Echocardiographic mitral valve prolapse, Doppler mitral regurgitation, blood pressure, anthropometry, and 4 psychobehavioral scales. Results Definite echocardiographic MVP prevalence was 0.6% overall and wassimilar across the 4 ethnicity/sex groups. Most participants (21 of 26, 80%) with definite echocardiographic MVP were unaware of their condition. Relative to persons with normal echocardiograms, those with echocardiographic MVP were taller (174.6 cm vs 171.0 cm, P < .01), leaner (26.7 mm vs 37.4 mmsum of triceps and subscapular skinfolds, P < .01), had lower body mass index (22.0 kg/m(2) vs 26.2 kg/m(2), P < .01), and more often has Doppler mitral regurgitation (34.8% vs 11.8%, P < .01). Women with echocardiographic MVP had higher ethnicity-adjusted hostility scores (19.9 vs 16.1, P < .05) than women with no MVP. Among 111 (2.7%) of 4136 participants reporting prior physician diagnosis of MVP, only 5 (0.45%) of 111 had definite echocardiographic MVP. Conclusions These data document a low prevalence of definite echocardiographic MVP and suggest a constellation of anthropometric, physiologic, and psychobehavioral characteristics in young adults with echocardiographic MVP. Most definite echocardiographic MVP diagnoses were discordant with self-reported MVP status, and false-positive diagnoses of echocardiographic MVP were made more often in women and whites.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:31:09