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Titolo:
Impact of nocturnal fall in blood pressure on early cardiovascular changesin essential hypertension
Autore:
Cuspidi, C; Lonati, L; Sampieri, L; Macca, G; Valagussa, L; Zaro, T; Michev, I; Fusi, V; Leonetti, G; Zanchetti, A;
Indirizzi:
Univ Milan, Ctr Fisiol Clin & Ipertens, I-20122 Milan, Italy Univ Milan Milan Italy I-20122 iol Clin & Ipertens, I-20122 Milan, Italy Univ Milan, Ist Clin Med Gen & Terapia Med, I-20122 Milan, Italy Univ Milan Milan Italy I-20122 d Gen & Terapia Med, I-20122 Milan, Italy Osped Maggiore, IRCCS, I-20122 Milan, Italy Osped Maggiore Milan Italy I-20122 Maggiore, IRCCS, I-20122 Milan, Italy Osped S Luca, IRCCS, Ist Auxol, Milan, Italy Osped S Luca Milan ItalyOsped S Luca, IRCCS, Ist Auxol, Milan, Italy
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 9, volume: 17, anno: 1999,
pagine: 1339 - 1344
SICI:
0263-6352(199909)17:9<1339:IONFIB>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR HYPERTROPHY; TARGET-ORGAN DAMAGE; CIRCADIAN VARIATION; REPRODUCIBILITY; DIPPERS; MASS; VARIABILITY; NONDIPPERS; THICKNESS;
Keywords:
ambulatory blood pressure monitoring; carotid wall thickness; dippers; hypertension; left ventricular hypertrophy; non-dippers;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Cuspidi, C Univ Milan, Ctr Fisiol Clin & Ipertens, Via F Sforza 35, I-20122 Milan, Italy Univ Milan Via F Sforza 35 Milan Italy I-20122 22 Milan, Italy
Citazione:
C. Cuspidi et al., "Impact of nocturnal fall in blood pressure on early cardiovascular changesin essential hypertension", J HYPERTENS, 17(9), 1999, pp. 1339-1344

Abstract

Objective To evaluate in a selected population of subjects with a recent diagnosis of hypertension whether a blunted nocturnal fall in blood pressureis associated with more advanced cardiac and vascular damage. Methods One hundred and eleven recently diagnosed and never-treated patients with mild essential hypertension underwent 24-h ambulatory blood pressure monitoring (ABPM), echocardiography and carotid ultrasonography,Results The 78 patients with normal (>10%) night-time fall in systolic blood pressure (SBP) and diastolic blood pressure (DBP) (dippers) were similarto the 33 patients with a small (less than or equal to 10%) fall (non-dippers) for age, sex, body surface area, smoking habit, clinic and 24-h blood pressure. There were no differences between dippers and non-dippers in leftventricular mass index (104 versus 105 g/m(2)), common carotid internal diameter (5.8 versus 5.9 mm), intima-media thickness (0.66 versus 0.64 mm) and carotid plaques prevalence (25 versus 29%), Furthermore, no differences were found in the correlation of daytime and night-time SEP and DBP with left ventricular mass and carotid wall thickness. When the 77 men and 34 womenwere analysed separately, similar results were obtained. Conclusion These results suggest that a blunted reduction in night-time blood pressure does not play a major role in the development of cardiovascular changes during the early phase of essential hypertension. J Hypertens 1999, 17:1339-1344 (C) Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:52:05